Results 101 to 110 of about 1,922,046 (318)

Tumor Microenvironment-Responsive Drug Delivery Based on Polymeric Micelles for Precision Cancer Therapy: Strategies and Prospects

Biomedicines
In clinical practice, drug therapy for cancer is still limited by its inefficiency and high toxicity. For precision therapy, various drug delivery systems, including polymeric micelles self-assembled from amphiphilic polymeric materials, have been ...
Zhu Jin, Majdi Al Amili, Shengrong Guo
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Precision Farming by Cotton Producers in Six Southern States: Results from the 2001 Southern Precision Farming Survey

Precision Farming by Cotton Producers in Six Southern States: Results from the 2001 Southern Precision Farming Surveycotton, precision farming, survey, Agribusiness, Farm Management, Production Economics, Research and Development/Tech Change/Emerging ...
Shurley, W. Donald, Roberts, Roland K., Martin, Steven W., English, Burton C., Larson, James A., Larkin, Sherry L., Goodman, W. Robert, Reeves, Jeanne M., Marra, Michele C., Cochran, Rebecca L.   +9 more
core  

A dynamics-driven approach to precision machines design for micro-manufacturing and its implementation perspectives

, 2008
Precision machines are essential elements in fabricating high quality micro products or micro features and directly affect the machining accuracy, repeatability and efficiency.
Cheng, K, Huo, D
core  

Design of a five-axis ultra-precision micro-milling machine—UltraMill. Part 1: Holistic design approach, design considerations and specifications

, 2009
High-accuracy three-dimensional miniature components and microstructures are increasingly in demand in the sector of electro-optics, automotive, biotechnology, aerospace and information-technology industries.
Wardle, F, Cheng, K, Huo, D
core   +1 more source

A Review of Nanostructure Coating Techniques to Achieve High-Precision Optical Fiber Sensing Applications

Nanomanufacturing
Optical fiber sensors have emerged as a critical sensing technology across various fields due to their advantages, including high potential bandwidth, electrical isolation that is safe for utilization in electrically hazardous environments, high ...
Sooping Kok, YunIi Go, Xu Wang, Dennis Wong   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Intensity of Precision Agriculture Technology Adoption by Cotton Producers

Many studies on the adoption of precision technologies have generally used logit models to explain the adoption behavior of individuals. This study investigates factors affecting the intensity of precision agriculture technologies adopted by cotton ...
Roberts, Roland K., Martin, Steven W., English, Burton C., Larson, James A., Larkin, Sherry L., Lambert, Dayton M., Reeves, Jeanne M., Marra, Michele C., Paxton, Kenneth W., Mishra, Ashok K., Chintawar, Sachin   +10 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Precision Farming by Cotton Producers in Eleven Southern States: Results from the 2005 Southern Precision Farming Survey

Precision Farming by Cotton Producers in Eleven Southern States: Results from the 2005 Southern Precision Farming Surveycotton, precision farming, survey, Agribusiness, Farm Management, Production Economics, Research and Development/Tech Change/Emerging ...
Shurley, W. Donald, Roberts, Roland K., Martin, Steven W., English, Burton C., Larson, James A., Larkin, Sherry L., Goodman, W. Robert, Reeves, Jeanne M., Marra, Michele C., Cochran, Rebecca L., Paxton, Kenneth W.   +10 more
core