Results 81 to 90 of about 1,922,046 (318)
Frontiers in NeuroscienceAlzheimer’s disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide, affecting over 55 million people globally, with numbers expected to rise dramatically.
Wided Hechkel, Abdelhamid Helali
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ARTIFICIAL INTELLIGENCE IN BUSINESS OPERATIONS: EXPLORING PRODUCTIVITY AND ACCEPTANCE [PDF]
Annals of the University of Oradea: Economic ScienceThis paper will provide information on the impact of AI in daily life and work-related activities.Today, AI functionalities could nowadays transform businesses, playing a critical role in enhancing and improving decisions.
Ioana CIOFU +3 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Precision medicine: precision viticulture [PDF]
Bone Marrow Transplantation, 2022 openaire +2 more sources
What Precisely Is Precision Medicine? [PDF]
Trends in Pharmacological Sciences, 2017 In some ways, precision has been a goal for medicine since its first inception. Swallow this herb for a headache, but rub that poultice on a sore foot. Different ailments, everyone realized, require tailored treatments to be effective. As understanding of biological complexity improved, especially with the breakthrough of genetic sequencing, we gained ...
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Performance Evaluation of a B-type Natriuretic Peptide Assay Using the Alinity i Analyzer
Korean Journal of Clinical Laboratory ScienceB-type natriuretic peptide (BNP) is a crucial cardiac biomarker secreted from the ventricles in response to volume and pressure overload that is used widely in the diagnosis, prognosis, and risk assessments of heart failure.
Jae Yoon LEE +4 more
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Comparative analysis of Access PCT and Elecsys BRAHMS PCT assays for procalcitonin measurements [PDF]
Kosin Medical JournalBackground Procalcitonin (PCT) is a crucial biomarker for diagnosing sepsis and managing antibiotic therapy. This study evaluated the analytical performance and comparability of the Access PCT and Elecsys BRAHMS PCT assays.
Hyunji Choi +2 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source