Results 31 to 40 of about 1,239,816 (243)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A multidisciplinary team-based model of palliative treatment and nursing for a patient with end-stage cancer (多学科协作模式下1例肿瘤终末期患者的姑息治疗和护理)

中西医结合护理, 2022
A multidisciplinary team (MDT) is a professional group of surgeons, oncologists and other medical and nursing experts who makes decisions about a specific subject in a collective manner, and best course of treatment and nursing plan will be implemented ...
CUI Lishuan (崔立爽), LI Linlin (李琳琳), SONG Dun (宋钝), ZHANG Jinhua (张金华)   +3 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Investigation of the accuracy of BeiDou, QZSS and QZSS/BeiDou satellites configuration for short, medium and long baselines in the Asia-Pacific regions

Reports on Geodesy and Geoinformatics
The field of satellite navigation has seen significant advancements due to the fast development of multi-constellation Global Navigation Satellite Systems (GNSS).
Pirti Atinç
doaj   +1 more source

YOLOv11-RDTNet: A Lightweight Model for Citrus Pest and Disease Identification Based on an Improved YOLOv11n

Agronomy
Citrus pests and diseases severely impact fruit yield and quality. However, existing object detection models face limitations in complex backgrounds, target occlusion, and small target recognition, and they struggle to be efficiently deployed on resource-
Qiufang Dai, Shiyao Liang, Zhen Li, Shilei Lyu, Xiuyun Xue, Shuran Song, Ying Huang, Shaoyu Zhang, Jiaheng Fu   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Research on the TF–IDF algorithm combined with semantics for automatic extraction of keywords from network news texts

Journal of Intelligent Systems
As the number of online news texts continues to increase, the algorithm of automatic keyword extraction becomes a key content in facilitating users’ fast access to the desired content.
Wang Yan
doaj   +1 more source

Development of a Precision Map of the Village Based using Drone Imagery to Improve the Quality of Planning

Jurnal Pembangunan dan Alam Lestari
Integrating drone technology into rural planning offers transformative advancements in geographic mapping by providing exceptional precision, efficiency, and accessibility.
Gunawan Prabowo, Mohammad Bisri, Rosihan Asmara, Ari Sugeng, Suprapedi , Abdul Aziz   +5 more
doaj   +1 more source

Precision of laboratory methods based on protein solubility in quality control of heat treated feedstuffs [PDF]

Hemijska Industrija, 2012
Some of feedstuffs used as raw materials in feed industry contain anti-nutritional factors that negatively influence their quality. One of them is soybean, which is, prior to oil extraction, referred to as full-fat soybean (FFSB).
Palić Dragan V., Morey Liesl, Modika Kedibone Y., Kokić Bojana M., Đuragić Olivera M., Spasevski Nedeljka J.   +5 more
doaj   +1 more source