Results 41 to 50 of about 1,304,316 (294)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Gigi Tiruan Kaitan Presisi untuk Kasus Unilateral Free End Rahang Bawah

open access: yesJournal of Dentistry Indonesia, 2015
It is not easy to find a good and comfortable design for a lower unilateral free end denture (Class II Kennedy), while a fixed bridge is contraindicated, and removable denture is not convenient, because a bar is esxisting on the floor of the mouth.
Laura Susanti Himawan
doaj   +1 more source

My Therapist Has Paws and a Tail – Impact of Having Pets on the Psychosocial Wellbeing of Pet Owners Residing In an Urban Area of Kancheepuram District Tamil Nadu

open access: yesNational Journal of Community Medicine, 2021
Introduction: Pet attachment plays an important role in human’s mental health, well-being, and quality of life. This study examined the human attachment to their pets and their stress reduction because of their pets among urban area of Kancheepuram ...
Keerthana Ramesh, Umadevi R
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

A cast partial obturator with hollow occlusal shim and semi-precision attachment

open access: yesIndian Journal of Dental Research, 2018
A maxillofacial patient's quality of life is distorted and social integration becomes difficult. An obturator is a maxillofacial prosthesis used to close a congenital or acquired tissue defect, primarily of the hard palate and/or contiguous alveolar/soft-
Mukesh Kumar Singhal   +3 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The emergence of the disorganised/disoriented (D) attachment classification, 1979-1982 [PDF]

open access: yes, 2015
This article examines the emergence of the concept of infant disorganized/disoriented attachment, drawing on published and archival texts and interviews.
Duschinsky, Robbie
core   +3 more sources

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Attachment Styles Within the Coach-Athlete Dyad: Preliminary Investigation and Assessment Development [PDF]

open access: yes, 2013
The present preliminary study aimed to develop and examine the psychometric properties of a new sport-specific self-report instrument designed to assess athletes’ and coaches’ attachment styles. The development and initial validation comprised three main
Jowett, Sophia   +2 more
core   +1 more source

Combined Prosthesis with Extracoronal Castable Precision Attachments

open access: yesCase Reports in Dentistry, 2013
Satisfactory restoration in a patient with a partially edentulous situation can be challenging especially when unilateral or bilateral posterior segment of teeth is missing.
Naveen Gupta   +3 more
doaj   +1 more source

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