Results 61 to 70 of about 262,394 (295)

Energy resolution of alpha particles in a microbulk Micromegas detector at high pressure Argon and Xenon mixtures [PDF]

, 2009
The latest Micromesh Gas Amplification Structures (Micromegas) are achieving outstanding energy resolution for low energy photons, with values as low as 11% FWHM for the 5.9 keV line of $^{55}$Fe in argon/isobutane mixtures at atmospheric pressure.
A. Tomás, Alkhazov, Avignone, Dolbeau, E. Ferrer-Ribas, F. Iguaz, Giomataris, Giomataris, Giomataris, I. Giomataris, I.G. Irastorza, Knoll, Luscher, Ounalli, P. Salin, Ph. Gorodetzky, T. Dafni   +16 more
core   +3 more sources

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Laboratory rotational ground state transitions of NH$_3$D$^+$ and CF$^+$ [PDF]

, 2016
Aims. This paper reports accurate laboratory frequencies of the rotational ground state transitions of two astronomically relevant molecular ions, NH3D+ and CF+. Methods. Spectra in the millimeter-wave band were recorded by the method of rotational state-
Brünken, Sandra, Kluge, Lars, Schlemmer, Stephan, Stoffels, Alexander   +3 more
core   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Three-Dimensional Printed Attachments: Analysis of Reproduction Accuracy Compared to Traditional Attachments

Applied Sciences
Background: The aim of this study was to propose a new 3D printing method for attachment production and compare the reproduction accuracy of traditional attachments with the proposed 3D-printed attachments. Methods: A standardized 3D model attachment was
Angela Mirea Bellocchio, Elia Ciancio, Ludovica Ciraolo, Serena Barbera, Riccardo Nucera   +4 more
doaj   +1 more source

Using parse features for preposition selection and error detection [PDF]

, 2010
We evaluate the effect of adding parse features to a leading model of preposition usage. Results show a significant improvement in the preposition selection task on native speaker text and a modest increment in precision and recall in an ESL error ...
Chodorow, Martin, Foster, Jennifer, Tetreault, Joel   +2 more
core   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

MODELING OF TECHNOLOGY PROCESSES OF DIAGNOSTICS AND CONTROL OF NC WORKING

Известия высших учебных заведений: Нефть и газ, 2015
A problem of improvement of precision of engineering products NC working is considered. A solution is offered to solve this problem through ensuring the introducing the on-line corrections into the machines actuators path motion.
R. Yu. Nekrasov, U. S. Putilova, A. I. Starikov, I. V. Soloviev, K. V. Kuskov   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Field performance of a pneumatic row crop planter equipped with active toothed coulter for direct planting of corn in wheat residue

Spanish Journal of Agricultural Research, 2013
In this research effects of active toothed coulter on planter penetration in semi-dried soils covered with previous wheat (triticum aestivum) residue was studied. Therefore, effects of three levels of speed ratio (coulter peripheral speed/tractor forward
J. Nejadi, M. H. Raoufat
doaj   +1 more source