Results 51 to 60 of about 262,394 (295)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Contemporary Clinical Dentistry, 2014 Marginal mandibular resection to treat neoplasms leads to loss of alveolar bone and teeth at the affected side. Consequently patient suffers with poor masticatory performance and esthetic disfigurement, which we need to restore with the help of ...
Kailas Mundhe, Gunjan Pruthi, Veena Jain
doaj +1 more source
Psych, 2022 Strategically timed trauma- and attachment-informed psychotherapy to address underlying emotional wounds, paired with ketamine administered in precision-calibrated doses to ensure high-entropy brain states, may be key to improving the quality and ...
Sherry-Anne Muscat +3 more
doaj +1 more source
Non-invasive quantification of lower limb mechanical alignment in flexion [PDF]
, 2014 Objective: Non-invasive navigation techniques have recently been developed to determine mechanical femorotibial alignment (MFTA) in extension. The primary aim of this study was to evaluate the precision and accuracy of an image-free navigation system ...
Deakin, Angela +3 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Using a Probabilistic Class-Based Lexicon for Lexical Ambiguity Resolution
, 2000 This paper presents the use of probabilistic class-based lexica for disambiguation in target-word selection. Our method employs minimal but precise contextual information for disambiguation. That is, only information provided by the target-verb, enriched
Prescher, Detlef +2 more
core +5 more sources
Quick Detection of High-degree Entities in Large Directed Networks [PDF]
, 2014 In this paper, we address the problem of quick detection of high-degree entities in large online social networks. Practical importance of this problem is attested by a large number of companies that continuously collect and update statistics about ...
Avrachenkov, Konstantin +3 more
core +5 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Enhancing EEG-based attachment style prediction: unveiling the impact of feature domains
Frontiers in PsychologyIntroductionAttachment styles are crucial in human relationships and have been explored through neurophysiological responses and EEG data analysis. This study investigates the potential of EEG data in predicting and differentiating secure and insecure ...
Ilan Laufer, Dor Mizrahi, Inon Zuckerman
doaj +1 more source