Results 51 to 60 of about 73,971 (258)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The fetus/infant - mother as a co-evolving dyadic system and the development of attachment styles: an active inference perspective

Frontiers in Psychology
The mother–fetus/infant dyad constitutes a uniquely asymmetric biological and psychological system whose co-evolutionary dynamics we propose are most coherently understood within the Active Inference Framework (AIF).
Erica Santaguida, Giuseppe Pagnoni, Massimo Bergamasco   +2 more
doaj   +1 more source

MODELING OF TECHNOLOGY PROCESSES OF DIAGNOSTICS AND CONTROL OF NC WORKING

Известия высших учебных заведений: Нефть и газ, 2015
A problem of improvement of precision of engineering products NC working is considered. A solution is offered to solve this problem through ensuring the introducing the on-line corrections into the machines actuators path motion.
R. Yu. Nekrasov, U. S. Putilova, A. I. Starikov, I. V. Soloviev, K. V. Kuskov   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Field performance of a pneumatic row crop planter equipped with active toothed coulter for direct planting of corn in wheat residue

Spanish Journal of Agricultural Research, 2013
In this research effects of active toothed coulter on planter penetration in semi-dried soils covered with previous wheat (triticum aestivum) residue was studied. Therefore, effects of three levels of speed ratio (coulter peripheral speed/tractor forward
J. Nejadi, M. H. Raoufat
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Rehabilitasi Kasus Kelas I Kennedy Rahang Atas dengan Gigi Tiruan Kaitan Presisi (Precision Attachment)

Journal of Dentistry Indonesia, 2015
The most important reason for employing an extracoronal precision attachment in bilateral free end saddle denture is to fulfill the esthetic demands of the patient and the dentist. In this case, splinted crowns were fabricated for the remaining teeth (13,
Ruby Karyadi, Laura Susanti Himawan
doaj   +1 more source