Results 31 to 40 of about 365,969 (214)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Applied Physics ExpressWe developed a new etching technique using plasma generated at high pressure up to 9 atm. Operating at 9-atm pressure with a 30- μ m-diameter wire electrode, we demonstrated the generation of well-ordered plasma at a narrow gap of ∼10 μ m between the ...
Shotaro Matsumura +8 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Review Article: Inventory of platforms towards the design of a statically balanced six degrees of freedom compliant precision stage [PDF]
Mechanical Sciences, 2011 For many applications in precision engineering, a six degrees of freedom (DoF) compliant stage (CS) with zero stiffness is desirable, to deal with problems like backlash, friction, lubrication, and at the same time, reduce the actuation force.
A. G. Dunning, N. Tolou, J. L. Herder
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Scientific Reports, 2021 Fused silica with structured and continuous patterns is increasingly demanded in advanced imaging and illumination fields because of its excellent properties and functional performance.
Duo Li +5 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Cybersecure PMLSM Control System With Updatable Homomorphic Encryption
IEEE AccessThis study develops an encrypted position control system for an industrial-grade iron-cored permanent magnet linear synchronous motor (PMLSM) of Acc-max (Registered trademark) (NEOMAX Engineering Co., Ltd.) to enhance the security of control devices. The
Hiroaki Kawase +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Scientific Reports, 2022 Permanent-magnet small ball-end magnetorheological polishing method can be used to polish the small part with complex structure. However, the material removal rate of this method is low, which is difficult to improve the output and reduce the cost.
Jinchuan Tian +5 more
doaj +1 more source