β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Editorial: Plant biology for indoor vertical farming: a multi-discipline approach to controlled environment agriculture. [PDF]
Gauthier PPG, Marcelis LFM.
europepmc +1 more source
All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
wiley +1 more source
Direct video-based spatiotemporal deep learning for cattle lameness detection. [PDF]
Sohan MF +4 more
europepmc +1 more source
Multifunctional Tailoring of Fertilizer Composites Directly Derived From Phosphate Rock
A novel phosphorus‑sulfur mixed acid with urea (PSU) activation system converts low‑grade phosphate rock (LPR) into multifunctional fertilizer composites (MFCs). MFCs feature porous structures, high nutrient‑activation efficiency, superior slow‑release, and enhanced crop growth, offering a sustainable solution for integrated nutrient management and ...
Zenglian Qi +13 more
wiley +1 more source
Research on a Lightweight Recognition Model for Daily Cattle Behavior Toward Real-Time Monitoring. [PDF]
Yao J +6 more
europepmc +1 more source
Spectral Decomposition of Chemical Semantics for Activity Cliffs‐Aware Molecular Property Prediction
PrismNet mimics chemical intuition by functioning as a computational prism, refracting molecular graphs into complementary semantic views and spectral frequencies. This dual‐decomposition strategy effectively captures both global topologies and subtle “activity cliff” perturbations.
Chaoyang Xie +9 more
wiley +1 more source
Precision Livestock Farming Applied to Swine Farms-A Systematic Literature Review. [PDF]
Trabachini A +4 more
europepmc +1 more source
Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao +8 more
wiley +1 more source
Multi‐Tissue Genetic Regulation of RNA Editing in Pigs
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan +21 more
wiley +1 more source

