Results 1 to 10 of about 55,550 (98)

Detailed analysis on the reflection component for the black hole candidate MAXI J1348-630 [PDF]

, 2022
The black hole candidate MAXI J1348-630 was discovered on January 26th, 2019, with the Gas Slit Camera (GSC) on-board MAXI. We report a detailed spectral analysis of this source by using the archived data of NuSTAR.
Nan Jia, Xueshan Zhao, L. Gou, Javier A. García, Zhenxuan Liao, Ye Feng, Yufeng Li, Yuan Wang, Huixian Li, Jianfeng Wu   +9 more
semanticscholar   +1 more source

The black hole transient MAXI J1348–630: evolution of the compact and transient jets during its 2019/2020 outburst [PDF]

Monthly notices of the Royal Astronomical Society, 2021
We present the radio and X-ray monitoring campaign of the 2019/2020 outburst of MAXI J1348–630, a new black hole X-ray binary (BH XRB) discovered in 2019 January.
F. Carotenuto, S. Corbel, E. Tremou, T. Russell, A. Tzioumis, R. Fender, P. Woudt, S. Motta, J. Miller-Jones, J. Chauhan, A. Tetarenko, G. Sivakoff, I. Heywood, A. Horesh, A. J. van der Horst, E. Koerding, K. Mooley   +16 more
semanticscholar   +1 more source

Prevalence of DDC genotypes in patients with aromatic L-amino acid decarboxylase (AADC) deficiency and in silico prediction of structural protein changes.

Molecular Genetics and Metabolism, 2023
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive genetic disorder affecting the biosynthesis of dopamine, a precursor of both norepinephrine and epinephrine, and serotonin.
N. Himmelreich, M. Bertoldi, M. Alfadhel, M. Alghamdi, Y. Anikster, X. Bao, Fahad A. Bashiri, B. B. Zeev, Giovanni Bisello, A. Ceylan, Y. Chien, Y. Choy, S. Elsea, Lisa Flint, À. García-Cazorla, C. Gijavanekar, Emel Gümüş, M. Hamad, B. Hismi, T. Honzík, Oya Kuseyri Hübschmann, W. Hwu, Salvador Ibáñez-Micó, K. Jeltsch, N. Juliá-Palacios, C. Kasapkara, M. Kurian, K. Kuśmierska, Ning Liu, L. Ngu, John D. Odom, W. Ong, T. Opladen, Mari Oppebøen, P. Pearl, Belén Pérez, Roser Pons, A. Rygiel, Tan Ee Shien, R. Spaull, J. Sykut-Cegielska, B. Tabarki, Trine Tangeraas, B. Thöny, T. Wassenberg, Y. Wen, Y. Yakob, J. G. Yin, J. Zeman, N. Blau   +49 more
semanticscholar   +1 more source

Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development.

Molecules and Cells, 2022
Allele-specific expression of imprinted gene clusters is governed by gametic DNA methylation at master regulators called imprinting control regions (ICRs).
Aimee M. Juan, Yee Hoon Foong, J. L. Thorvaldsen, Y. Lan, N. Leu, J. Rurik, Li Li, Christopher J. Krapp, Casey L Rosier, J. Epstein, M. Bartolomei   +10 more
semanticscholar   +1 more source

Spectrum of DDC variants causing aromatic l-amino acid decarboxylase (AADC) deficiency and pathogenicity interpretation using ACMG-AMP/ACGS recommendations.

Molecular Genetics and Metabolism, 2022
Pathogenic variants in dopa decarboxylase (DDC), the gene encoding the aromatic l-amino acid decarboxylase (AADC) enzyme, lead to a severe deficiency of neurotransmitters, resulting in neurological, neuromuscular, and behavioral manifestations clinically
N. Himmelreich, R. Montioli, S. Garbade, Jeffrey W. Kopesky, S. Elsea, C. Carducci, C. Voltattorni, N. Blau   +7 more
semanticscholar   +1 more source

Melanin Synthesis Pathway Interruption: CRISPR/Cas9-mediated Knockout of dopa decarboxylase (DDC) in Harmonia axyridis (Coleoptera: Coccinellidae)

Journal of Insect Science, 2022
CRISPR/Cas9 technology is a very powerful genome editing tool and has been used in many insect species for functional genomics studies through targeted gene mutagenesis.
Meng-meng Wu, Xu Chen, Qingbiao Xu, L. Zang, Su Wang, Ming Li, D. Xiao   +6 more
semanticscholar   +1 more source

In Arabidopsis thaliana Cd differentially impacts on hormone genetic pathways in the methylation defective ddc mutant compared to wild type

Scientific Reports, 2021
DNA methylation plays an important role in modulating plant growth plasticity in response to stress, but mechanisms involved in such control need further investigation.
M. Pacenza, A. Muto, A. Chiappetta, L. Mariotti, E. Talarico, P. Picciarelli, E. Picardi, L. Bruno, M. B. Bitonti   +8 more
semanticscholar   +1 more source

Preclinical In Vitro Studies with 3D Spheroids to Evaluate Cu(DDC)2 Containing Liposomes for the Treatment of Neuroblastoma

Pharmaceutics, 2021
Preclinical in vitro studies of drug candidates for anticancer therapy are generally conducted on well-established 2D cell models. Unfortunately, these models are unable to mimic the properties of in vivo tumors.
F. Hartwig, M. Köll-Weber, R. Süss
semanticscholar   +1 more source

Tumor-Derived Extracellular Vesicles Promote Activation of Carcinoma-Associated Fibroblasts and Facilitate Invasion and Metastasis of Ovarian Cancer by Carrying miR-630

Frontiers in Cell and Developmental Biology, 2021
Ovarian cancer (OC) is a lethal gynecological malignancy. Extracellular vesicles (EVs) are crucial media in cell-to-cell communication by carrying microRNAs (miRs).
Yulan Cui, Deying Wang, Min Xie
semanticscholar   +1 more source

A giant X-ray dust scattering ring discovered with SRG/eROSITA around the black hole transient MAXI J1348–630

Astronomy & Astrophysics, 2021
We report the discovery of a giant dust scattering ring around the Black Hole transient MAXI J1348−630 with SRG/eROSITA during its first X-ray all-sky survey.
G. Lamer, A. Schwope, P. Predehl, I. Traulsen, J. Wilms, M. Freyberg   +5 more
semanticscholar   +1 more source