Results 1 to 10 of about 49,852 (116)

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets. [PDF]

open access: yesMedComm (2020)
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Li G   +13 more
europepmc   +2 more sources

Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase. [PDF]

open access: yesAdv Sci (Weinh)
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Guo L   +17 more
europepmc   +2 more sources

Serum Proteomic and Metabolomic Signatures of High Versus Low Physical Function in Octogenarians. [PDF]

open access: yesAging Cell
Circulating factors are strongly implicated in modulating biological aging. In this study we show that the serum proteomic and metabolomic profile of high functioning octogenarians suggests lower activation of SASP, preservation of the tryptophan‐kynurenic pathway, higher lipophosphatidyl cholines promoting mitochondrial function, and reduced ...
Ubaida-Mohien C   +11 more
europepmc   +2 more sources

Report 2021 of the DDC at DKRZ

open access: yes, 2022
This report provides statistics on the data downloads from the Reference Data Archive for climate model output hosted at the IPCC Data Distribution Centre (DDC) at DKRZ (http://ipcc.wdc-climate.de) for ...
Stockhause, Martina
core   +1 more source

HILT : a terminology mapping service with a DDC spine [PDF]

open access: yes, 2006
The role of DDC in the ongoing HILT (High-level Thesaurus) project is discussed. A phased initiative, funded by JISC in the UK, HILT addresses an issue of likely interest to anyone serving users wishing to cross-search or cross-browse groups of networked
Shiri, A.   +9 more
core   +1 more source

DDC AR6 Reference Data Archival of CMIP6 input datasets

open access: yes, 2023
A new directory and page with an overview over the data contained in the Reference Data Archive for AR6 at IPCC DDC Partner DKRZ was added.If you use this software, please cite it as ...
Stockhause, Martina   +2 more
core   +1 more source

IPCC-DDC at WDC Climate / DKRZ [PDF]

open access: yes, 2017
The talk given at the IPCC AR6 Data Workshop (19/20 September 2017) at DKRZ in Hambrug, Germany, between IPCC AR6 Working Group I and II TSUs and IPCC DDC Managers from BADC and WDCC/DKRZ gives an overview over the current data services within the IPCC ...
Lautenschlager, Michael   +5 more
core   +1 more source

Minutes of the DDC Managers Subgroup from November 2019 to June 2021

open access: yes, 2021
Minutes of the IPCC Task Group on Data (TG-DATA) subgroup for the DDC Managers. The period covered is from November 2019 to June 2021. The last set of minutes are for a meeting convened by CEDA and run by Metadatworks (who took the minutes for this ...
Martin Juckes
core   +1 more source

Building a DDC-annotated Corpus from OAI Metadata

open access: yes, 2010
Lösch M, Waltinger U, Horstmann W, Mehler A. Building a DDC-annotated Corpus from OAI Metadata. Journal of Digital Information. 2011;12(2)
Waltinger, Ulli   +4 more
core   +1 more source

DDC Variables for AR4

open access: yes, 2011
The document provides a table with variables long-term archived in the IPCC Data Distribution Centre's (DDC; http://www.ipcc-data.org) Reference Data Archive for the Fourth Assessment Report (AR4) including variable long names, short names and references
Juckes, Martin
core   +1 more source

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