Results 111 to 120 of about 507,954 (312)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Realization of a compact mercury ion microwave clock with frequency stability of 6.3 × 10− 16

Scientific Reports
The mercury ion microwave clock is considered to be one of the leading candidates for new generation satellite navigation atomic clocks due to its excellent long-term frequency stability, extremely low frequency drift rate, high reliability and good ...
Hao Liu, Yihe Chen, Jian Wang, Shuhong Huang, Longbao Xiang, Shicheng Yu, Chengbin Li, Lijun Du, Lei She   +8 more
doaj   +1 more source

High-Power, Wavelength-Locked 878.6 nm In-Band Pumped, Acoustic-Optically Q-Switched Nd:YVO₄ MOPA Laser With TEM₀₀ Mode

IEEE Photonics Journal, 2016
In this paper, a wavelength-locked 878.6-nm pumped acoustic-optically Q-switched Nd:YVO4 laser is presented. A master oscillator power amplifier configuration with two-stage amplifiers is employed to scale the output power.
Qiang Liu, Mingming Nie, Fuyuan Lu, Mali Gong   +3 more
doaj   +1 more source

Precision measurement of the mass and width of the W boson at CDF

, 2010
A precision measurement of the mass and width of the W boson is presented. The W bosons are produced in proton antiproton collisions occurring at a centre of mass energy of 1.96 TeV at the Tevatron accelerator.
Malik, S.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Illumination waveform optimization for time-of-flight range imaging cameras

, 2011
Time-of-flight range imaging sensors acquire an image of a scene, where in addition to standard intensity information, the range (or distance) is also measured concurrently by each pixel.
A. A. Dorrington, Payne, Andrew D., Dorrington, Adrian A., M. J. Cree, A. D. Payne, Cree, Michael J.   +5 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Influence of loudspeaker directivity on the measurement uncertainty

, 2011
One of the most significant aspects of a building’s acoustic behavior is the airborne sound insulation of the room façades, since this determines the protection of its inhabitants against environmental noise.
Sánchez Bote, José Luis, Díaz Sanchidrián, César, Pedrero González, Antonio, Ulin, Vladimir   +3 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Analysis of the Dick Effect for AI-Based Dynamic Gravimeters

Sensors
Atom interferometer (AI)-based dynamic gravimeters enable high-precision absolute gravity measurements, which are crucial for applications in geophysics, navigation, resource exploration, and metrology.
Wen-Zhang Wang, Xi Chen, Jin-Ting Li, Dan-Fang Zhang, Wei-Hao Xu, Jia-Yi Wei, Jia-Qi Zhong, Biao Tang, Lin Zhou, Jin Wang, Ming-Sheng Zhan   +10 more
doaj   +1 more source