Results 61 to 70 of about 446,257 (263)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

pH calibration allows accurate glucose detection in interstitial fluid via reverse iontophoresis

open access: yesNature Communications
Reverse iontophoresis (RI) is a promising non-invasive, wearable technology for the transdermal extraction of interstitial fluid (ISF), which contains rich biomarkers relevant to health status. Despite the advancement of wearable sensors, this technology
Wangwang Zhu   +18 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Improving the Precision of Weak Measurements by Postselection Measurement

open access: yesPhysical Review Letters, 2015
12 pages, 1 figure. V3: close to the published version. V2: analysis of squeezed coherent state and comparison between SNR and Fisher information added, supplemental material ...
Pang, Shengshi, Brun, Todd A.
openaire   +4 more sources

Design of an Achromatic Graphene Oxide Metalens with Multi-Wavelength for Visible Light

open access: yesPhotonics
Dispersion control is a critical aspect in nano-optical systems. Moreover, chromatic aberration significantly impacts image quality. Despite metasurfaces being a novel approach to tackle chromatic aberration in diffractive lenses, numerous challenges ...
Yuxi Chen   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Wavefront division digital holography

open access: yesAIP Advances, 2018
Digital holography (DH), mostly Mach-Zehnder configuration based, belongs to non-common path amplitude splitting interference imaging whose stability and fringe contrast are environmental sensitive.
Wenhui Zhang   +6 more
doaj   +1 more source

Capturing Electrocardiogram Signals from Chairs by Multiple Capacitively Coupled Unipolar Electrodes

open access: yesSensors, 2018
A prototype of an electrocardiogram (ECG) signal acquisition system with multiple unipolar capacitively coupled electrodes is designed and experimentally tested.
Zhongjie Hou   +5 more
doaj   +1 more source

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