Results 71 to 80 of about 3,580,467 (256)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Design of an Achromatic Graphene Oxide Metalens with Multi-Wavelength for Visible Light

open access: yesPhotonics
Dispersion control is a critical aspect in nano-optical systems. Moreover, chromatic aberration significantly impacts image quality. Despite metasurfaces being a novel approach to tackle chromatic aberration in diffractive lenses, numerous challenges ...
Yuxi Chen   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Wavefront division digital holography

open access: yesAIP Advances, 2018
Digital holography (DH), mostly Mach-Zehnder configuration based, belongs to non-common path amplitude splitting interference imaging whose stability and fringe contrast are environmental sensitive.
Wenhui Zhang   +6 more
doaj   +1 more source

Capturing Electrocardiogram Signals from Chairs by Multiple Capacitively Coupled Unipolar Electrodes

open access: yesSensors, 2018
A prototype of an electrocardiogram (ECG) signal acquisition system with multiple unipolar capacitively coupled electrodes is designed and experimentally tested.
Zhongjie Hou   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Data fusion for timber bundle volume measurement

open access: yes, 2019
In many industrial fields, the direct measurement of a specific parameter of interest can be too costly to be feasible. Using data from other parameters about the process, a data driven approach can instead be used for a cost-efficient estimation of the ...
Liguori C.   +4 more
core   +1 more source

Three-dimensional computer holography with phase space tailoring

open access: yesPhotoniX
Computer holography is a prominent technique for reconstructing customized three-dimensional (3D) diffraction fields. However, the quality of optical reconstruction remains a fundamental challenge in 3D computer holography, especially for the 3D ...
Runze Zhu   +3 more
doaj   +1 more source

A Stylus-Based Calibration Method for Robotic Belt Grinding Tools

open access: yesApplied Sciences
To address the tool calibration challenge in robotic systems equipped with grinding tools, this paper proposes a high-precision method utilizing a stylus assembly and the Particle Swarm Optimization (PSO) algorithm.
Di Chang   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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