Results 71 to 80 of about 2,901 (211)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Analytics in sustainable precision animal nutrition

open access: yesAnimal Frontiers, 2019
The global population, resource, and climate dynamics suggest we must improve sustainability of food production systems (Ohlsson, 2014; Kleinman et al., 2018). Improving livestock production sustainability is particularly important because a significant portion of the projected increases in global food demand is anticipated to come from livestock ...
Liebe, Douglas M., White, Robin R.
openaire   +3 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

open access: yesAdvanced Science
Doxorubicin (Dox), a potent antitumor drug, is linked to cardiac toxicity. Few mechanism‐based therapies against cardiotoxicity are available. Dysfunction in mitochondrial energy metabolism contributes to Dox‐induced cardiomyopathy.
Sitong Wan   +16 more
doaj   +1 more source

Precision Phosphorus Nutrition

open access: yesJournal of Applied Poultry Research, 1997
Abstract Formulating to meet minimum phosphorus requirements of the bird is not a simple matter. It is necessary to consider not only performance and environment but numerous interacting factors that can influence phosphorus metabolism and thus dietary requirement.
openaire   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Growth Characteristics, Blood Biochemistry, Histology, and Metabolic Profile of Muscle and Different Tissues: Toxicity Study of Deoxynivalenol

open access: yesFood Science of Animal Resources
Deoxynivalenol (DON) toxicity causes oxidative stress, immunological disorders, and gastrointestinal injury, thereby reducing animal survival and productivity.
Jin Young Jeong   +3 more
doaj   +1 more source

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