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Precision oncology in urothelial cancer [PDF]
Genomics-driven, precision medicine has been adopted in virtually every tumour type and underlies the significant advances in cancer management to date. The paradigm shift from the indiscriminate use of chemotherapeutics, to strategies that harness our mechanistic knowledge of cancer biology has led to profound clinical benefit for patients, and will ...
Ben Tran, Elizabeth Liow
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An Emerging Role for Radiation Oncology in Precision Oncology [PDF]
Precision medicine is rapidly evolving in the management of cancer, in an effort to deliver the right therapy to the right patient at the right time. The use of novel molecular or genetic signatures in decision making regarding local–regional management is in its infancy. In their recent work published in EBioMedicine, Cheng and colleagues developed
Sharad Goyal, Bruce G. Haffty
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The Future of Precision Oncology
Our understanding of the molecular mechanisms underlying cancer development and evolution have evolved rapidly over recent years, and the variation from one patient to another is now widely recognized. Consequently, one-size-fits-all approaches to the treatment of cancer have been superseded by precision medicines that target specific disease ...
Stuart L Rulten +2 more
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PRECISION ONCOLOGY- BASIC TO BEDSIDE
Basic science technologies and platforms have unraveled the molecular basis of carcinogenesis, both genetic and epigenetic events. Few of the events which are repeatedly observed and are actionable, gave birth to the science “Precision Oncology”.
Amit Verma
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Editorial: Precision Medicine in Oncology [PDF]
Angela Re +3 more
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Importance of genetic screens in precision oncology
Precision oncology aims to distinguish which patients are eligible for a specific treatment in order to achieve the best possible outcome. In the last few years, genetic screens have shown their potential to find the new targets and drug combinations as ...
Antonio Mulero-Sánchez +2 more
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Until recently, the clinical management of cancer heavily relied on anatomical and histopathological criteria, with ad hoc guidelines directing the therapeutic choices in specific indications.
Alexander Meisel
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Bioinformatics for precision oncology [PDF]
ISSN:1477 ...
Jochen Singer +7 more
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Heterogeneity in precision oncology
Abstract Precision oncology is a rapidly evolving concept that holds great promise in cancer treatment. However, a cancer complexity attributed to genomic and acquired tumour heterogeneity limits treatment effectiveness and increases toxicity. These limitations refer to both systemic therapies and radiotherapy, which are two mainstays
Bartłomiej Tomasik +4 more
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Precision oncology is a rapidly evolving field that uses advanced technologies to deliver personalized cancer care based on a patient’s unique genetic and clinical profile.
Bahareh Farasati Far
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