Results 211 to 220 of about 307,974 (304)

Evaluation of Current Evidence on the Efficacy of Esketamine in Treating Substance-Use Disorders in Patients With Treatment-Resistant Depression (TRD): A Narrative Review. [PDF]

Cureus
Shelke S, Thummalapally RR.
europepmc   +1 more source

Wet Ball Milling Synthesis of Iron Oxide Nanoparticles for High‐Efficiency, Controllable Magnetic Hyperthermia in Ovarian Cancer

Advanced Materials Technologies, EarlyView.
A wet ball‐milling method is presented to synthesize iron magnetic nanoparticles and evaluate their magnetic hyperthermia performance. Optimized particles (∼270 nm, Ms ∼114 emu/g) achieve ∼50°C heating under clinically safe alternating magnetic fields, while pulsed‐field operation enables controlled temperature regulation (∼30°C).
Shahriar Mostufa, Bahareh Rezaei, Md Shahriar, Karla Mercedes Paz González, Anil Kumar, Changxue Xu, Yun Suk Eo, Ioannis H. Karampelas, Jenifer Gómez‐Pastora, Rui He, Kai Wu   +10 more
wiley   +1 more source

An Industry Perspective on Key Considerations for the ICH S13 Guidance: Nonclinical Safety Evaluations of Oligonucleotide-Based Therapeutics. [PDF]

Int J Toxicol
Sisler JD, Andersson P, Brown A, Harbison C, Irrechukwu O, Lightfoot H, Maes M, Mukherjee S, Parry JD, Schumacher J, Westlind Johnsson A, Yang Y, Harper TA.   +12 more
europepmc   +1 more source

Bamboo Medical Application: A State‐of‐the‐Art Review

Advanced Materials Technologies, EarlyView.
This review presents a structured classification of bamboo's current use in healthcare. It organizes applications into medical textiles and medical devices, with further divisions based on function and level of invasiveness. It also examines material utilization based on bamboo's structural role, highlighting how it supports both protective and ...
Haymanot Beza Lamesgin, Koosje van der Stoel, Vera Popovich, Paul Breedveld   +3 more
wiley   +1 more source

Antifibrotic Strategies Targeting Phosphodiesterase-4 in Idiopathic Pulmonary Fibrosis: Molecular Mechanisms and Clinical Translation. [PDF]

Clin Pharmacol
Ma Q, Zhou S, Zhi X, Luo C, Zhu Z, Zhang X, Liu X.   +6 more
europepmc   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

Plant-Derived Nanocarriers for Drug Delivery: A Unified Framework Integrating Extracellular Vesicles, Engineered Phytocarriers, Hybrid Platforms, and Bioinspired Systems. [PDF]

Plants (Basel)
Segneanu AE, Mogoşanu GD, Bejenaru C, Kostici R, Bejenaru LE.   +4 more
europepmc   +1 more source

Innovation Policy and the Economy, Volume 6 [PDF]

Adrian H. B. Gottschalk, Ernst R. Berndt, Matthew W. Strobeck   +2 more
core  

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source