Results 341 to 350 of about 1,044,728 (382)

Applications of Preclinical MRI/MRS in the Evaluation of Drug Efficacy and Safety

2015
The drug discovery process is a series of interrelated, bidirectional steps culminating in the declaration of an investigational new drug. Upon selection of a disease target and initiation of drug screening and chemistry efforts, secondary and tertiary assays to assess the efficacy and safety of potential lead candidates or develop biomarkers to ...
Lauren Keith, Thomas M. Bocan, David Thomasson   +2 more
openaire   +2 more sources

Preclinical evaluation of drug effects on testicular functions

Pharmacology & Therapeutics, 1979
B. Schenck, F. Neumann
openaire   +3 more sources

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation.

Journal of Hepatology, 2016
L. Allweiss, S. Gass, K. Giersch, Anne Groth, J. Kah, T. Volz, G. Rapp, A. Schöbel, A. Lohse, S. Polywka, S. Pischke, E. Herker, M. Dandri, M. Lütgehetmann   +13 more
semanticscholar   +1 more source

Nanostructured lipidic carriers for dual drug delivery in the management of psoriasis: Systematic optimization, dermatokinetic and preclinical evaluation

Journal of Drug Delivery Science and Technology, 2020
A. Qadir, M. Aqil, Athar Ali, M. H. Warsi, M. Mujeeb, F. Ahmad, Sayeed Ahmad, S. Beg   +7 more
semanticscholar   +1 more source

Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies

Ca-A Cancer Journal for Clinicians, 2022
Paolo Tarantino, Roberto Carmagnani Pestana, Shanu Modi   +2 more
exaly  

Noninvasive cardiac output monitoring with bioreactance as an alternative to invasive instrumentation for preclinical drug evaluation in beagles.

Journal of pharmacological and toxicological methods, 2011
P. Heerdt, Christa L Wagner, Marissa DeMais, J. Savarese   +3 more
semanticscholar   +1 more source

Significance of neurochemical parameters in the preclinical evaluation of neuroleptic drugs

Pharmacology & Therapeutics, 1979
Antonio Groppetti, F. Cattabeni, Giorgio Racagni, Corrado L. Galli   +3 more
openaire   +3 more sources

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Abstract 2667: Molecular profiling guided human PDX tumor model selection for preclinical drug evaluation

, 2012
Jie Cai, Xiaomin Song, Mengmeng Yang, Dawei Chen, Jia-Peng Deng, Henry Li, Yiyou Chen, J. Wery, Taiping Chen   +8 more
semanticscholar   +1 more source

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly