Results 71 to 80 of about 918,697 (241)

Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E–based Antibody–Drug Conjugate for Treatment of Nectin-4–expressing Cancers [PDF]

, 2023
Wei Zhou, Peng Fang, Dongan Yu, Hongyuan Ren, Meng You, Long Yin, Fei Mei, Huikai Zhu, Zhenzhen Wang, Hui Xu, Yuxia Cao, Xiaowei Sun, Xiaohong Xu, Jianjun Bi, Jin Wang, Lanping Ma, Xin Wang, Lin Chen, Yongliang Zhang, Xiaowei Cen, Xi Zhu, Liguang Lou, Datao Liu, Xiaoding Tan, Jinliang Yang, Tao Meng, Jingkang Shen   +26 more
openalex   +1 more source

Preclinical Evaluation of Drug-Eluting Stents for Peripheral Applications [PDF]

, 2004
Robert S. Schwartz, Elazer R. Edelman, Andrew Carter, Nicolas A.F. Chronos, Campbell Rogers, Keith A. Robinson, Ron Waksman, Lindsay Machan, Judah Weinberger, Robert L. Wilensky, Jennifer Goode, O.D. Hottenstein, Bram D. Zuckerman, Renu Virmani   +13 more
openalex   +1 more source

Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model [PDF]

, 2020
Nahee Park, Kamal Pandey, Sei Kyung Chang, Ah‐Young Kwon, Young Bin Cho, Jin Hur, Nar Bahadur Katwal, Seung‐Ki Kim, Seung Ah Lee, Gun Woo Son, Jong Min Jo, Hee Jung Ahn, Yong Wha Moon   +12 more
openalex   +1 more source

Patient-Derived 3D Models for Preclinical Drug Response Evaluation in Neuroblastoma [PDF]

, 2023
Stephanie J. Gros, Zhen Huo, Remo Bilang, Claudiu T. Supuran, Nicolas von der Weid, Stefan Holland‐Cunz, Iván Martín, Manuele Giuseppe Muraro   +7 more
openalex   +1 more source

Nanosized ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery against vitiligo: formulation optimization, in vitro evaluation and preclinical assessment

Journal of drug targeting (Print), 2016
The present investigation aimed for the development and characterization of ethosomes-based hydrogel formulations of methoxsalen for enhanced topical delivery and effective treatment against vitiligo.
B. Garg, N. Garg, S. Beg, Bhupinder Singh, O. Katare   +4 more
semanticscholar   +1 more source

In Vitro and In Vivo Test Methods for the Evaluation of Gastroretentive Dosage Forms

Pharmaceutics, 2019
More than 50 years ago, the first concepts for gastroretentive drug delivery systems were developed. Despite extensive research in this field, there is no single formulation concept for which reliable gastroretention has been demonstrated under different
Felix Schneider, Mirko Koziolek, Werner Weitschies   +2 more
doaj   +1 more source

Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation [PDF]

, 2020
Vijesh Kumar Yadav, Yan‐Jiun Huang, Thomashire A. George, Po‐Li Wei, Maryam Rachmawati Sumitra, Ching-Liang Ho, Tzu‐Hao Chang, Alexander T.H. Wu, Hsu-Shan Huang   +8 more
openalex   +1 more source

Multitask CapsNet: An Imbalanced Data Deep Learning Method for Predicting Toxicants

ACS Omega, 2021
Yiwei Wang, Binyou Wang, Jie Jiang, Jianmin Guo, Jia Lai, Xiao-Yuan Lian, Jianming Wu   +6 more
doaj   +1 more source

Improving the predictive accuracy of efficacy evaluation using tumor orthotopic transplant and resection model

Frontiers in Pharmacology
Preclinical efficacy evaluation and tumor drug sensitivity analysis are two main applications of efficacy evaluation. Preclinical efficacy evaluation is to predict whether candidate drugs or therapies may improve patient outcomes in clinical trials ...
Xiaoxi Li, Lingli Luo, Hui Qian
doaj   +1 more source

Design, Synthesis, and Preclinical Evaluations of Novel 4-Substituted 1,5-Diarylanilines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Drug Candidates [PDF]

, 2012
Lian-Qi Sun, Lei Zhu, Keduo Qian, Bingjie Qin, Li Huang, Chin Ho Chen, Kuo‐Hsiung Lee, Lan Xie   +7 more
openalex   +1 more source