Results 21 to 30 of about 6,433,487 (363)

Lymphoma: current status of clinical and preclinical imaging with radiolabeled antibodies. [PDF]

Eur J Nucl Med Mol Imaging, 2017
England CG, Rui L, Cai W.
europepmc   +2 more sources

DNA nanomaterials for preclinical imaging and drug delivery. [PDF]

J Control Release, 2016
Jiang D, England CG, Cai W.
europepmc   +2 more sources

Preclinical Lymphatic Imaging [PDF]

Molecular Imaging and Biology, 2010
Noninvasive in vivo imaging of lymphatic vessels and lymphatic nodes is expected to fulfill the purpose of analyzing lymphatic vessels and their function, understanding molecular mechanisms of lymphangiogenesis and lymphatic spread of tumors, and utilizing lymphatic molecular markers as a prognostic or diagnostic indicator. In this review, we provide a
Fan Zhang, Fan Zhang, Gang Niu, Guangming Lu, Xiaoyuan Chen   +4 more
openaire   +3 more sources

Covalent ¹⁸F-Radiotracers for SNAPTag: A New Toolbox for Reporter Gene Imaging

Pharmaceuticals, 2021
There is a need for versatile in vivo nuclear imaging reporter systems to foster preclinical and clinical research. We explore the applicability of the SNAPTag and novel radiolabeled small-molecule ligands as a versatile reporter gene system for in vivo ...
Sophie Stotz, Gregory D. Bowden, Jonathan M. Cotton, Bernd J. Pichler, Andreas Maurer   +4 more
doaj   +1 more source

Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy

European Journal of Nuclear Medicine and Molecular Imaging, 2022
Fibroblast activation protein (FAP) is a membrane-bound protease that has limited expression in normal adult tissues but is highly expressed in the tumor microenvironment of many solid cancers.
D. Zboralski, A. Hoehne, A. Bredenbeck, A. Schumann, Minh Nguyen, Eberhard Schneider, J. Ungewiss, M. Paschke, Christian Haase, J. L. von Hacht, T. Kwan, K. Lin, Jan Lenore, T. Harding, Jim J. Xiao, A. Simmons, A. Mohan, N. Beindorff, U. Reineke, C. Smerling, F. Osterkamp   +20 more
semanticscholar   +1 more source

Biomarkers in preclinical cancer imaging [PDF]

European Journal of Nuclear Medicine and Molecular Imaging, 2015
In view of the trend towards personalized treatment strategies for (cancer) patients, there is an increasing need to noninvasively determine individual patient characteristics. Such information enables physicians to administer to patients accurate therapy with appropriate timing.
Bernsen, M.R., Kooiman, K., Segbers, M., Leeuwen, F.W.B. van, Jong, M. de   +4 more
openaire   +5 more sources

Measurement of Aβ Amyloid Plaques and Tau Protein in Postmortem Human Alzheimer’s Disease Brain by Autoradiography Using [¹⁸F]Flotaza, [¹²⁵I]IBETA, [^124/125I]IPPI and Immunohistochemistry Analysis Using QuPath

Biomedicines, 2023
High-resolution scans of immunohistochemical (IHC) stains of Alzheimer’s disease (AD) brain slices and radioligand autoradiography both provide information about the distribution of Aβ plaques and Tau, the two common proteinopathies in AD.
Rommani Mondal, Yasmin K. Sandhu, Vallabhi M. Kamalia, Brooke A. Delaney, Amina U. Syed, Grace A. H. Nguyen, Taylor R. Moran, Roz R. Limpengco, Christopher Liang, Jogeshwar Mukherjee   +9 more
doaj   +1 more source

Optimizing dual energy cone beam CT protocols for preclinical imaging and radiation research. [PDF]

Br J Radiol, 2017
Schyns LE, Almeida IP, van Hoof SJ, Descamps B, Vanhove C, Landry G, Granton PV, Verhaegen F.   +7 more
europepmc   +3 more sources

Synthesis and Biological Evaluation of a Radiolabeled PET (Positron Emission Tomography) Probe for Visualization of In Vivo α-Fucosidase Expression

Pharmaceuticals, 2021
The acidic hydrolase α-fucosidase (AF) is a biomarker for maladies such as cancer and inflammation. The most advanced probes for α-fucosidase are unfortunately constrained to ex vivo or in vitro applications.
Jonathan Cotton, Chris Marc Goehring, Anna Kuehn, Andreas Maurer, Kerstin Fuchs, Bernd J. Pichler   +5 more
doaj   +1 more source

Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling

Alzheimer’s Research & Therapy, 2021
Background To better understand the etiology and pathomechanisms of Alzheimer’s disease, several transgenic animal models that overexpress human tau or human amyloid-beta (Aβ) have been developed. In the present study, we generated a novel transgenic rat
Thomas Filip, Severin Mairinger, Joerg Neddens, Michael Sauberer, Stefanie Flunkert, Johann Stanek, Thomas Wanek, Nobuyuki Okamura, Oliver Langer, Birgit Hutter-Paier, Claudia Kuntner   +10 more
doaj   +1 more source