Results 41 to 50 of about 231,020 (192)
Preclinical and Translational PET/MR Imaging [PDF]
Journal of Nuclear Medicine, 2014 Combined PET and MR imaging (PET/MR imaging) has progressed tremendously in recent years. The focus of current research has shifted from technologic challenges to the application of this new multimodal imaging technology in the areas of oncology, cardiology, neurology, and infectious diseases.
H. F. Wehrl +9 more
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Semi-automated Image Processing for Preclinical Bioluminescent Imaging [PDF]
Journal of Applied Bioinformatics & Computational Biology, 2015 Bioluminescent imaging is a valuable noninvasive technique for investigating tumor dynamics and specific biological molecular events in living animals to better understand the effects of human disease in animal models. The purpose of this study was to develop and test a strategy behind automated methods for bioluminescence image processing from the ...
Nikolai V, Slavine, Roderick W, McColl
openaire +2 more sources
Noninvasive molecular imaging of neuroinflammation [PDF]
, 2011 Inflammation is a highly dynamic and complex adaptive process to preserve and restore tissue homeostasis. Originally viewed as an immune-privileged organ, the central nervous system (CNS) is now recognized to have a constant interplay with the innate and
Jacobs, A.H. (Andreas) +13 more
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Oxygen saturation imaging using LED-based photoacoustic system [PDF]
, 2021 Oxygen saturation imaging has potential in several preclinical and clinical applications. Dual-wavelength LED array-based photoacoustic oxygen saturation imaging can be an affordable solution in this case. For the translation of this technology, there is
Steenbergen, Wiendelt +11 more
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Standardisation of preclinical PET/CT protocols across multiple research centres [PDF]
, 2020 Preclinical Positron Emission Tomography/Computed Tomography (PET/CT) is a well-established non-invasive imaging tool for studying disease development/progression, the development of novel radiotracers and pharmaceuticals for clinical applications ...
McDougald, Wendy Anne
core +1 more source
Scientific Reports, 2021 Exposure to antibiotic treatment has been associated with increased vulnerability to various psychiatric disorders. However, a research gap exists in understanding how adolescent antibiotic therapy affects behavior and cognition.
Anouk C. Tengeler +7 more
doaj +1 more source
3rd TPCF Preclinical Symposium Imaging(TPIS 2020)
Frontiers in Biomedical Technologies, 2020 The path of discovering/designing a molecule to developing a novel drug could take up to an average of 12 years and costs around $1 billion (USD). Preclinical phase is a major step on this path and is the part where scientists perform additional studies ...
3rd TPCF Preclinical Symposium Imaging (TPIS 2020)
doaj
[124I]IBETA: A New Aβ Plaque Positron Emission Tomography Imaging Agent for Alzheimer’s Disease
Molecules, 2022 Several fluorine-18-labeled PET β-amyloid (Aβ) plaque radiotracers for Alzheimer’s disease (AD) are in clinical use. However, no radioiodinated imaging agent for Aβ plaques has been successfully moved forward for either single-photon emission computed ...
Grace A.H. Nguyen +2 more
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Molecular Imaging, 2017 Objective: Imaging animal models of Alzheimer disease (AD) is useful for the development of therapeutic drugs and understanding AD. Transgenic Swedish hAPPswe Tg2576 mice are a good model of β-amyloid plaques.
Robert A. Coleman PhD +4 more
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Communications Biology, 2022 Nuclear magnetic resonance spectroscopy-based tissue metabolomics is used to define detailed temporal signatures of acute and chronic inflammation in cutaneous delayed-type hypersensitivity reaction.
Laimdota Zizmare +7 more
doaj +1 more source