Results 1 to 10 of about 594,856 (170)
Current Opinion in Rheumatology, 2015 Systemic lupus erythematosus (SLE) is often preceded by immune dysregulation and clinical manifestations below the threshold for SLE classification. This review discusses current and evolving concepts about the preclassification period of SLE, including clinical and mechanistic observations, and potential avenues for early identification and ...
Rebecka, Bourn, Judith A, James
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Clinical and Experimental Dental Research, 2023 The purpose of this technical report is to present two novel experimental implant designs to boost data generation in preclinical in vivo research.
Andreas Stavropoulos +3 more
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Preclinical models of schizophrenia [PDF]
International Journal of Neuropsychopharmacology, 2013 Introducción (CINP).
Frazer, Alan, Artigas, Francesc
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Frontiers in Immunology, 2022 Background & AimsRheumatoid arthritis (RA) is a prototypic autoimmune disease causing inflammatory polyarthritis that affects nearly 1% of the population.
Emily N. Kowalski +4 more
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A 3D-printed vanperio educative dental model – A review report of its chairside evaluation
Journal of Indian Society of Periodontology, 2023 Background: Patient education and demonstration of osseous defects by teachers and clinicians are difficult even though there are different models made up of metal, plastic, plaster, stone, and acrylic.
Kharidhi Laxman Vandana +2 more
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Industrial Psychiatry Journal, 2021 Background: The worldwide COVID-19 pandemic has significantly altered our life. Doctors more so than the general public because of their involvement in managing the COVID-infected individuals, some of them 24/7 end in burnout. Burnout in doctors can lead
V Pooja +5 more
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Preclinical biomarker qualification [PDF]
Experimental Biology and Medicine, 2017 Biomarkers are ubiquitously used within drug development programs in both nonclinical species and in humans to assess safety and efficacy of novel compounds. To routinely apply such novel biomarkers with certainty, a well-defined data package is necessary for review and endorsement by regulatory agencies including the US Food and Drug Administration ...
John-Michael, Sauer, Amy C, Porter
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Frontiers in Physics, 2021 Cerenkov luminescence is a blue-weighted emission of light produced by a vast array of clinically approved radioisotopes and LINAC accelerators. When β particles (emitted during the decay of radioisotopes) are present in a medium such as water or tissue,
Benedict Mc Larney +7 more
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4th Internatinal TPCF Preclinical Imaging Symposium
Frontiers in Biomedical Technologies, 2021 Due to the huge costs and time spent for development of new drugs (around almost $ 1 billion (USD) and 12 Years), investing on the preclinical phase of drug development could be regarded as a great investment for de-risking the clinical phases ...
4th Internatinal TPCF Preclinical Imaging
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Tannins in the Treatment of Diabetic Neuropathic Pain: Research Progress and Future Challenges
Frontiers in Pharmacology, 2022 Diabetes mellitus and its consequences continue to put a significant demand on medical resources across the world. Diabetic neuropathic pain (DNP) is a frequent diabetes mellitus chronic microvascular outcome.
Norsuhana Omar +2 more
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