Results 31 to 40 of about 789,487 (311)

MRI as a Tool to Assess Interstitial Cystitis Associated Bladder and Brain Pathologies

open access: yesDiagnostics, 2021
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic, often incapacitating condition characterized by pain seeming to originate in the bladder in conjunction with lower urinary tract symptoms of frequency and urgency, and consists of a wide ...
Rheal A. Towner   +3 more
doaj   +1 more source

Evaluating real-patient learning in medical education – Hungarian validation of the Manchester Clinical Placement Index

open access: yesFrontiers in Medicine, 2023
IntroductionThe Manchester Clinical Placement Index (MCPI) is an instrument to measure medical undergraduates’ real-patient learning in communities of practice both in hospital and in GP placements.
Szabolcs Fábry   +11 more
doaj   +1 more source

Preclinical Knowledge Retention by MBBS Students during Their Clinical Years: An Observational Study to Analyze Preparedness towards National Exit Test [PDF]

open access: yesIndian Journal of Medical Biochemistry
Aim and background: One of the challenges to be faced by MBBS students completing their final year henceforth is to face the national exit test (NeXT) to be eligible to practice and start postgraduate studies. The objectives were to compare the retention
Veena Bhaskar S Gowda   +2 more
doaj   +1 more source

The employment of vaccinia virus for colorectal cancer treatment: A review of preclinical and clinical studies

open access: yesHuman Vaccines & Immunotherapeutics, 2022
Colorectal cancer (CRC) is one of the leading malignancies that causes death worldwide. Cancer vaccines and oncolytic immunotherapy bring new hope for patients with advanced CRC. The capability of vaccinia virus (VV) in carrying foreign genes as antigens
Qiaoyun Ling   +4 more
doaj   +1 more source

Targeting Sphingolipids for Cancer Therapy

open access: yesFrontiers in Oncology, 2021
Sphingolipids are an extensive class of lipids with different functions in the cell, ranging from proliferation to cell death. Sphingolipids are modified in multiple cancers and are responsible for tumor proliferation, progression, and metastasis ...
Osmel Companioni   +4 more
doaj   +1 more source

Radiotherapy and erlotinib combined: review of the preclinical and clinical evidence

open access: yesFrontiers in Oncology, 2012
Epidermal growth factor receptor is often overexpressed in tumors and has been associated with poor prognosis in some cancer types. The introduction of inhibitors of epidermal growth factor receptor, such as erlotinib and cetuximab, represents an ...
Vivek Krishan Mehta
doaj   +1 more source

From Bedside to the Bench—A Call for Novel Approaches to Prognostic Evaluation and Treatment of Empyema

open access: yesFrontiers in Pharmacology, 2022
Empyema, a severe complication of pneumonia, trauma, and surgery is characterized by fibrinopurulent effusions and loculations that can result in lung restriction and resistance to drainage.
Sophia Karandashova   +3 more
doaj   +1 more source

3rd TPCF Preclinical Symposium Imaging(TPIS 2020)

open access: yesFrontiers in Biomedical Technologies, 2020
The path of discovering/designing a molecule to developing a novel drug could take up to an average of 12 years and costs around $1 billion (USD). Preclinical phase is a major step on this path and is the part where scientists perform additional studies ...
3rd TPCF Preclinical Symposium Imaging (TPIS 2020)
doaj  

MR histology reveals tissue features beneath heterogeneous MRI signal in genetically engineered mouse models of sarcoma

open access: yesFrontiers in Oncology
PurposeTo identify significant relationships between quantitative cytometric tissue features and quantitative MR (qMRI) intratumorally in preclinical undifferentiated pleomorphic sarcomas (UPS).Materials and methodsIn a prospective study of genetically ...
Stephanie J. Blocker   +10 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

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