Results 11 to 20 of about 789,487 (311)

5th Internatinal TPCF Preclinical Imaging Symposium

Frontiers in Biomedical Technologies, 2023
Preclinical imaging is the visualization of living animals for research purposes, such as drug development. Imaging modalities have long been crucial to the researcher in observing changes, either at the organ, tissue, cell, or molecular level, in ...
5th Internatinal TPCF Preclinical Imaging
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6th Internatinal TPCF Preclinical Imaging Symposium

Frontiers in Biomedical Technologies
As we step into 2023, the landscape of translational medicine continues to evolve, revealing the profound importance of preclinical imaging in bridging the gap between laboratory discoveries and clinical applications.
6 th Internatinal TPCF Preclinical Imaging
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7th International Conference on Preclinical Imaging Applications

Frontiers in Biomedical Technologies
As we embrace 2024, the field of translational medicine stands at an exciting crossroads where innovation, collaboration, and cutting-edge technology converge.
7 th International TPCF Preclinical Imaging
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Clinical relevance assessment of animal preclinical research (RAA) tool: development and explanation. [PDF]

, 2021
Only a small proportion of preclinical research (research performed in animal models prior to clinical trials in humans) translates into clinical benefit in humans.
Gurusamy, KS, Barron, Carly C, McHugh, TD, Moher, D., Avey, MT, Osborne, N., Gluud, C, Barron, Carly C., Jell, G, van Laarhoven, Kees, Ahmed, Irfan, Moher, D, Loizidou, Marilena, Katakam, K, Loizidou, M., Ritskes-Hoitinga, Merel, Dwek, M, Lalu, Manoj, Laarhoven, K. van, Avey, M., Ritskes-Hoitinga, M., Katakam, Kiran, Montroy, Joshua, Moher, David, Ahmed, I, Gurusamy, K.S., Avey, Marc T., Barron, CC, Gurusamy, K., Davidson, B, Vollert, J, Loizidou, M, Jell, G., van Laarhoven, K, Dwek, M., Vollert, Jan, Ritskes-Hoitinga, M, Davidson, Brian, Osborne, NJ, Gluud, C., Montroy, J, Lalu, M, McHugh, T.   +42 more
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Retinal capillary nonperfusion in preclinical diabetic retinopathy [PDF]

, 2023
The aim of the study was to identify retinal microvascular changes using optical coherence tomography angiography (OCTA) in type 2 diabetes (T2D) patients with preclinical retinopathy identified by ultra-widefield fundus photography (UWF-FP).
Foote, Katharina, Martinho, António Cunha-Vaz, Almeida, Ana Catarina, Cunha-Vaz, José, Santos, Torcato, Marques, Inês Pereira, Rocha, Ana Cláudia, Mendes, Luís, Reste-Ferreira, Débora, Santos, Ana Rita   +9 more
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Preclinical progression of neurodegenerative diseases [PDF]

, 2018
2018-08Neurodegenerative diseases are disorders that are characterized by a progressive decline of the motor and/or cognitive function caused by a selective loss of neurons within the central nervous system.
Hashizume, Atsushi, Sahashi, Kentaro, Katsuno, Masahisa, Iguchi, Yohei   +3 more
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Preclinical characterisation of fingolimod as a potential therapeutic agent for stroke [PDF]

, 2022
Stroke is the leading cause for death and disability worldwide, and the search for novel drug treatments has been affected by repeated clinical trial failures.
Diaz Diaz, Andrea C.
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In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]

, 2012
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo, Groiss, Volker, Schneider, Katja, Renier J Brentjens, Nadia Terziyska, Harald Ehrhardt, Jeremias, I., Brentjens, Renier J., Farkasova, K., Katja Schneider, Volker Groiss (106787), Katarina Farkasova (106794), Ehrhardt, Harald, Wagner, E., Renier J. Brentjens (106801), Quintanilla-Martinez, Leticia, Martin Horstmann (45040), Ehrhardt, H., Ernst Wagner (60760), Wagner, Ernst, Leticia Quintanilla-Martinez (33277), Terziyska, N., Katja Schneider (106791), Horstmann, M., Brentjens, R.J., Catarina Castro Alves, Quintanilla-Martinez, L., Zur Stadt, U., Horstmann, Martin, Schneider, K., Ogris, M., Manfred Ogris, Alves, C.C., Nadia Terziyska (106777), Terziyska, Nadia, Jeremias, Irmela, Groiss, V., Irmela Jeremias (106806), Volker Groiss, Udo zur Stadt, Martin Horstmann, Farkasova, Katarina, Ernst Wagner, Irmela Jeremias, Ogris, Manfred, Udo zur Stadt (106803), Catarina Castro Alves (106783), Manfred Ogris (60759), Castro Alves, Catarina, Katarina Farkasova, Leticia Quintanilla-Martinez, Harald Ehrhardt (106798)   +51 more
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Preclinical translation of therapeutic interventions for tendon injury

, 2021
Killian, Megan L.The burden of injury to tendon and the attachment between tendon and bone (i.e., the tendon-bone attachment) on quality of life, disability, health care, and the economy is significant.
Locke, Ryan C.
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Interregional compensatory mechanisms of motor functioning in progressing preclinical neurodegeneration. [PDF]

, 2013
Understanding brain reserve in preclinical stages of neurodegenerative disorders allows determination of which brain regions contribute to normal functioning despite accelerated neuronal loss.
Scheller, Elisa, Peter, J, Peter, Jessica, Scheller, E., Peter, J., Abdulkadir, Ahmed, Frackowiak, Richard S. J., Frackowiak, R.S., Klöppel, Stefan, Tabrizi, S.J., Frackowiak, Richard S.J., Abdulkadir, A, Tabrizi, SJ, Frackowiak, RS, Scheller, E, Klöppel, S., Tabrizi, Sarah J., Abdulkadir, A., Klöppel, S   +18 more
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