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Status Go for Preclinical Imaging
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.
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Preclinical Imaging of Prostate Cancer. [PDF]
Prostate cancer remains a major cause of mortality and morbidity, affecting millions of men, with a large percentage expected to develop the disease as they reach advanced ages. Treatment and management advances have been dramatic over the past 50 years or so, and one aspect of these improvements is reflected in the multiple advances in diagnostic ...
Olkowski C +4 more
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XNAT-PIC: Extending XNAT to Preclinical Imaging Centers. [PDF]
Molecular imaging generates large volumes of heterogeneous biomedical imagery with an impelling need of guidelines for handling image data. Although several successful solutions have been implemented for human epidemiologic studies, few and limited ...
Zullino S +4 more
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Preclinical Lymphatic Imaging [PDF]
Noninvasive in vivo imaging of lymphatic vessels and lymphatic nodes is expected to fulfill the purpose of analyzing lymphatic vessels and their function, understanding molecular mechanisms of lymphangiogenesis and lymphatic spread of tumors, and utilizing lymphatic molecular markers as a prognostic or diagnostic indicator. In this review, we provide a
Fan, Zhang +3 more
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In vivo molecular imaging in preclinical research
AbstractIn vivo molecular imaging is a research field in which molecular biology and advanced imaging techniques are combined for imaging molecular-level biochemical and physiological changes that occur in a living body. For biomolecular imaging, the knowledge of molecular biology, cell biology, biochemistry, and physiology must be applied.
Su Jin Kim, Ho-Young Lee
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In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo +51 more
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Interregional compensatory mechanisms of motor functioning in progressing preclinical neurodegeneration. [PDF]
Understanding brain reserve in preclinical stages of neurodegenerative disorders allows determination of which brain regions contribute to normal functioning despite accelerated neuronal loss.
Scheller, Elisa +18 more
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Although brain research has taken important strides in recent decades, the interaction and coupling of its different physiological levels is still not elucidated.
Tudor M. Ionescu +7 more
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Lossy Image Compression in a Preclinical Multimodal Imaging Study
AbstractThe growing use of multimodal high-resolution volumetric data in pre-clinical studies leads to challenges related to the management and handling of the large amount of these datasets. Contrarily to the clinical context, currently there are no standard guidelines to regulate the use of image compression in pre-clinical contexts as a potential ...
Francisco Cunha +9 more
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Low-Dose Imaging in a New Preclinical Total-Body PET/CT Scanner
Ionizing radiation constitutes a health risk to imaging scientists and study animals. Both PET and CT produce ionizing radiation. CT doses in pre-clinical in vivo imaging typically range from 50 to 1,000 mGy and biological effects in mice at this dose ...
Cesar Molinos +19 more
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