Results 21 to 30 of about 231,020 (192)

Preclinical Imaging of siRNA Delivery

open access: yesAustralian Journal of Chemistry, 2016
Small interfering RNA (siRNA) is emerging as a class of therapeutic with extremely high potential, particularly in the field of oncology. Despite this growing interest, further understanding of how siRNA behaves in vivo is still required before significant uptake into clinical application.
Fletcher, Nicholas   +2 more
openaire   +5 more sources

Preclinical Imaging of Prostate Cancer. [PDF]

open access: yesSemin Nucl Med, 2023
Prostate cancer remains a major cause of mortality and morbidity, affecting millions of men, with a large percentage expected to develop the disease as they reach advanced ages. Treatment and management advances have been dramatic over the past 50 years or so, and one aspect of these improvements is reflected in the multiple advances in diagnostic ...
Olkowski C   +4 more
europepmc   +3 more sources

Status Go for Preclinical Imaging

open access: yes, 2020
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.
openaire   +2 more sources

XNAT-PIC: Extending XNAT to Preclinical Imaging Centers. [PDF]

open access: yesJ Digit Imaging, 2022
Molecular imaging generates large volumes of heterogeneous biomedical imagery with an impelling need of guidelines for handling image data. Although several successful solutions have been implemented for human epidemiologic studies, few and limited ...
Zullino S   +4 more
europepmc   +2 more sources

Preclinical Lymphatic Imaging [PDF]

open access: yesMolecular Imaging and Biology, 2010
Noninvasive in vivo imaging of lymphatic vessels and lymphatic nodes is expected to fulfill the purpose of analyzing lymphatic vessels and their function, understanding molecular mechanisms of lymphangiogenesis and lymphatic spread of tumors, and utilizing lymphatic molecular markers as a prognostic or diagnostic indicator. In this review, we provide a
Fan, Zhang   +3 more
openaire   +2 more sources

In vivo molecular imaging in preclinical research

open access: yesLaboratory Animal Research, 2022
AbstractIn vivo molecular imaging is a research field in which molecular biology and advanced imaging techniques are combined for imaging molecular-level biochemical and physiological changes that occur in a living body. For biomolecular imaging, the knowledge of molecular biology, cell biology, biochemistry, and physiology must be applied.
Su Jin Kim, Ho-Young Lee
openaire   +3 more sources

Synthesis and Evaluation of Compound Targeting α7 and β2 Subunits in Nicotinic Acetylcholinergic Receptor

open access: yesMolecules, 2023
Nicotinic acetylcholine receptors (nAChRs) are involved in various central nervous system functions and have also been implicated in several neurodegenerative disorders.
Karanveer Singh   +5 more
doaj   +1 more source

Preclinical Ultrasound Imaging—A Review of Techniques and Imaging Applications [PDF]

open access: yesFrontiers in Physics, 2020
Ultrasound imaging is a well-established clinical imaging technique providing real-time, quantitative anatomical and physiological information in humans. The lack of ionizing radiation and relative low purchase and maintenance costs results in it being one of the most frequently used clinical imaging techniques with increasing use for guiding ...
Moran, Carmel, Thompson, Adrian
openaire   +3 more sources

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice. [PDF]

open access: yes, 2012
Xenograft mouse models represent helpful tools for preclinical studies on human tumors. For modeling the complexity of the human disease, primary tumor cells are by far superior to established cell lines.
zur Stadt, Udo   +51 more
core   +1 more source

Striatal and prefrontal D2R and SERT distributions contrastingly correlate with default-mode connectivity

open access: yesNeuroImage, 2021
Although brain research has taken important strides in recent decades, the interaction and coupling of its different physiological levels is still not elucidated.
Tudor M. Ionescu   +7 more
doaj   +1 more source

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