Advanced Healthcare Materials, EarlyView.We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He +10 more
wiley +1 more source
Looking at the fraction with Annexin V⁺ and propidium iodide⁺: insights into cell death types from preclinical studies in solid and haematological cancers. [PDF]
ApoptosisHassan SN, Ahmad F.
europepmc +1 more source
Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery
Advanced Healthcare Materials, EarlyView.This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han +5 more
wiley +1 more source
Preclinical Studies on Plant Based-Antacid Formulations as New Therapies for Gastro-Oesophageal Reflux Disease. [PDF]
Pharmaceuticals (Basel)De Cicco P +12 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han +10 more
wiley +1 more source
The translational potential of salvinorin A: systematic review and meta-analysis of preclinical studies. [PDF]
Transl PsychiatryZürrer WE +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour +6 more
wiley +1 more source
Retraction Note: Preclinical studies of toxicity and anti-cholangiocarcinoma activity of the standardized capsule formulation of atractylodes lancea (Thunb.) DC. [PDF]
BMC Complement Med TherPlengsuriyakarn T +3 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello +2 more
wiley +1 more source
Anti-Diabetic Potential of Corn (<i>Zea mays</i> L.) Silk: A Systematic Review and Meta-Analysis of Preclinical Studies. [PDF]
Prev Nutr Food SciBohari B +3 more
europepmc +1 more source