Results 241 to 250 of about 814,690 (301)

Molecular Basis of Anxiety: A Comprehensive Review of 2014-2024 Clinical and Preclinical Studies. [PDF]

open access: yesInt J Mol Sci
Merkouris E   +10 more
europepmc   +1 more source

Preclinical Studies

ICU Director, 2012
Sepsis remains a major cause of morbidity and mortality in hospitalized patients. The pathophysiology of sepsis involves complex interactions between microbial pathogens and the host immune system. Stem cells have the potential to both directly regenerate tissue by virtue of their pluripotency and mitigate injury and inflammation through paracrine ...
Yinggang Zhu, Xiaomei Feng, Jae-Woo Lee
openaire   +1 more source

Corneal stroma regeneration: Preclinical studies

Experimental Eye Research, 2021
Corneal grafting is one of the most common and successful forms of human tissue transplantation in the world, but the need for corneal grafting is growing and availability of human corneal donor tissue to fulfill this increasing demand is not assured worldwide.
Jorge L, Alió Del Barrio   +4 more
openaire   +2 more sources

Preclinical studies of glimepiride

Drugs of Today, 1998
The treatment of NIDDM is advancing on a number of fronts, ranging from the understanding of the mechanisms of action of existing agents to the development of new drugs. Glimepiride, the most recently U.S. approved sulfonylurea, is evaluated for its pancreatic and extrapancreatic activities in addition to safety, when compared with glibenclamide in ...
C, Nguyen, J, Pan, M A, Charles
openaire   +2 more sources

Oncolytic virus preclinical toxicology studies

Journal of Applied Toxicology, 2022
AbstractWith the ever‐emerging concerns of patient safety during medical care, the search for treatments as safe as possible is a priority, especially when focusing on cancer treatment of which therapies often go hand in hand with severe side effects.
Agnija Rasa, Pēteris Alberts
openaire   +2 more sources

Capecitabine: Preclinical Pharmacology Studies

Investigational New Drugs, 2000
Capecitabine (N4-pentyloxycarbonyl-5'-deoxy-5-fluorocytidine) is a novel fluoropyrimidine carbamate, which was designed to be sequentially converted to 5-fluorouracil (5-FU) by three enzymes located in the liver and in tumors; the final step is the conversion of 5'-deoxy-5-fluorouridine (5'-DFUR) to 5-FU by thymidine phosphorylase (dThdPase) in tumors.
openaire   +2 more sources

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