Results 41 to 50 of about 65,030 (220)

Gut microbiota-metabolite interactions meditate the effect of dietary patterns on precocious puberty

iScience
Summary: Precocious puberty, a pediatric endocrine disorder classified as central precocious puberty (CPP) or peripheral precocious puberty (PPP), is influenced by diet, gut microbiota, and metabolites, but the specific mechanisms remain unclear.
Ying Wang, Chuandi Jin, Hongying Li, Xiangrong Liang, Changying Zhao, Nan Wu, Min Yue, Lu Zhao, Han Yu, Qian Wang, Yongsheng Ge, Meiling Huo, Xin Lv, Lehai Zhang, Guoping Zhao, Zhongtao Gai   +15 more
doaj   +1 more source

Developmental differences in cortical bone structure in chimpanzee and human femora reflect early locomotor independence in humans

The Anatomical Record, EarlyView.
Abstract The cortical bone structure of long bone diaphyses changes throughout growth via skeletal modeling and has important implications for bone strength and structural integrity. Ontogenetic trends in diaphyseal structure have been identified in both chimpanzees and humans but it is not yet clear how these trends compare given notable differences ...
Karen R. Swan, Rachel Ives, Zewdi J. Tsegai, Louise T. Humphrey   +3 more
wiley   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Abdominal imaging in precocious puberty in girls [PDF]

Precocious puberty in girls is defined by the appearance of secondary sex characteristics before the age of 8 years. Precocious puberty is either peripheral or central. In most cases, the cause of central precocious puberty is unknown.
Sofia, Carmelo, Napolitano, Marcello, Ključevšek, Damjana, Bruno, Costanza, Smets, Anne M., Lobo, Maria-Luisa   +5 more
core   +2 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Precocious puberty in children [PDF]

International Journal of Pediatric Endocrinology, 2013
To determine the etiology of precocious puberty in children and to compare the clinical and laboratory parameters of central and peripheral precocious puberty.Cross-sectional study.Endocrine Clinic at National Institute of Child Health, Karachi, from January 2009 to December 2011.Children presenting with precocious puberty were included.
Atta, Irum, laghari, Taj, Khan, Yasir, Lone, Saira, Ibrahim, Mohsina, Raza, Jamal   +5 more
openaire   +2 more sources

Causes and Types of Precocious Puberty in North-West Iran [PDF]

, 2013
Objective: Precocious puberty is of concern because of the underlying disorders, the short adult stature, and the psychosocial difficulties. This study was carried out in order to evaluate the characteristics of children referred to pediatric ...
Shiva, Siamak, Shiva, Shadi, Fayyazi, Afshin, Melikian, Armen   +3 more
core   +2 more sources

Dietary pattern and precocious puberty risk in Chinese girls: a case-control study

Nutrition Journal
Background The role of dietary intake on precocious puberty remains unclear. This study aimed to investigate the association between the amount and frequency of dietary intake and the risk of precocious puberty in Chinese girls.
Qiuyun Gu, Youmei Wu, Zhuowei Feng, Yimeng Chai, Shan Hou, Zhiping Yu, Xiuhua Shen   +6 more
doaj   +1 more source

Guilt, Uncertainty, Education Needs, and Knowledge of Mothers With Children Experiencing Precocious Puberty

Global Pediatric Health, 2022
Introduction. Childhood illnesses not only affect the child, but also the family members. Objective. The purpose of this study was to investigate the guilt, uncertainty, education needs, and knowledge of mothers with children experiencing precocious ...
Hye Young Ahn RN, PhD, Kyung Hee Yoo RN, MSN, Mi Ryeong Song RN, PhD   +2 more
doaj   +1 more source

Dose‐Dependent Efficacy of Radioiodine Therapy in Pediatric Graves’ Disease: A Retrospective Study of Hypothyroidism Risk and the Predictive Role of Thyroid Hormone Parameters

iRADIOLOGY, EarlyView.
RAI therapy demonstrated time‐dependent efficacy in pediatric Graves' disease, with gradually increasing treatment success and hypothyroidism incidence during follow‐up. Higher planned activity (≥ 0.15 mCi/g) was associated with a higher successful rate than lower planned activity (< 0.15 mCi/g), and LASSO analysis identified FT3 and TSH as candidate ...
Xiaoxue Tian, Dan Zhang, Yihui Wang, Lujie Cao, Junpu Jian, Jiangyan Liu, Changping Liang, Yinzhong Wang, Yonghui Chen   +8 more
wiley   +1 more source