Results 51 to 60 of about 1,731 (272)

Preconditioned Conjugate Gradient Method for Solution of Large Finite Element Problems on CPU and GPU

Journal of Telecommunications and Information Technology, 2016
In this article the preconditioned conjugate gradient (PCG) method, realized on GPU and intended to solution of large finite element problems of structural mechanics, is considered.
Sergiy Yu. Fialko , Filip Zeglen
doaj   +1 more source

Preconditioning Technique for an Image Deblurring Problem with the Total Fractional-Order Variation Model

Mathematical and Computational Applications, 2023
Total fractional-order variation (TFOV) in image deblurring problems can reduce/remove the staircase problems observed with the image deblurring technique by using the standard total variation (TV) model. However, the discretization of the Euler–Lagrange
Adel M. Al-Mahdi
doaj   +1 more source

Nonsymmetric multigrid preconditioning for conjugate gradient methods

, 2012
We numerically analyze the possibility of turning off post-smoothing (relaxation) in geometric multigrid when used as a preconditioner in conjugate gradient linear and eigenvalue solvers for the 3D Laplacian. The geometric Semicoarsening Multigrid (SMG) method is provided by the hypre parallel software package.
Bouwmeester, Henricus, Dougherty, Andrew, Knyazev, Andrew V.   +2 more
openaire   +2 more sources

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

Conjugate-gradient preconditioning methods for shift-variant PET image reconstruction [PDF]

IEEE Transactions on Image Processing, 1999
Gradient-based iterative methods often converge slowly for tomographic image reconstruction and image restoration problems, but can be accelerated by suitable preconditioners. Diagonal preconditioners offer some improvement in convergence rate, but do not incorporate the structure of the Hessian matrices in imaging problems.
Fessler, Jeffrey A., Booth, Scott D.
openaire   +4 more sources

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

The Numerical Solution of Singularly Perturbed Nonlinear Partial Differential Equations in Three Space Variables: The Adaptive Explicit Inverse Preconditioning Approach

Modelling and Simulation in Engineering, 2019
Critical comments on the complexity of computational systems and the basic singularly perturbed (SP) concepts are given. A class of several complex SP nonlinear elliptic equations arising in various branches of science, technology, and engineering is ...
Anastasia-Dimitra Lipitakis
doaj   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Application of Exact Newton Optimisation to the Maximum Likelihood Ensemble Filter

Tellus: Series A, Dynamic Meteorology and Oceanography
The Newton method is used for optimisation in the maximum likelihood ensemble filter (MLEF) to improve analysis convergence and accuracy. The proposed method is compared against the original method using the conjugate gradient (CG) method preconditioned ...
Takeshi Enomoto, Saori Nakashita
doaj   +1 more source

Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism

Advanced Science, EarlyView.
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards, Ella‐May Hards, Sofia N. dos Santos, Hannah E. Greenwood, Madeleine E. George, Andrea Emanuelli, Muhammet Tanc, Thomas R. Eykyn, Timothy H. Witney   +8 more
wiley   +1 more source