Results 101 to 110 of about 79,614 (239)

A complete response with daratumumab, venetoclax, azacitidine and dexamethasone in a heavily pre-treated, chemo-refractory early T-precursor acute lymphoblastic leukemia/lymphoma patient.

Annals of Hematology
Early T-precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) is a rare and aggressive subtype of T-cell leukemia with poor prognosis and resistance to standard treatments.
Sureyya Yigit Kaya, Mehrad Vatani, Rima Akil, Tansel Cakir, S. Maral, L. Kaynar, Ömür Gökmen Sevindik   +6 more
semanticscholar   +1 more source

The significance of PAX5 in Merkel cell carcinoma

The Journal of Pathology, Volume 266, Issue 1, Page 81-94, May 2025.
Abstract Merkel cell carcinoma (MCC) is a highly malignant skin cancer that expresses epithelial‐, neuroendocrine‐, and lymphoid‐associated genes. Here, we focused on B‐cell differentiation, which is characterised by the coexpression of PAX5 and TdT. PAX5 is the master regulator of B‐cell commitment and is expressed in 65% of MCC cases.
Emil Chteinberg, Julia Kolarova, Julia Vogt, Amanda Macamo, Felix Bormann, Helene Kretzmer, Ernst Jan Speel, Joost van den Oord, Christof Schneider, Stephan Stilgenbauer, Jürgen C Becker, Véronique Winnepenninckx, Erik Biessen, Martin Zenke, Anna Kordelia Kurz, Reiner Siebert, Axel zur Hausen   +16 more
wiley   +1 more source

A Challenging Case of Gamma Delta T-Cell Lymphoma with Precursor T-Cells and Marked Eosinophilia: A Case Report

Case Reports in Oncology, 2020
Gamma-delta (γδ) T-cell lymphomas are very rare and aggressive neoplasms. We describe here a challenging case of γδ T-cell neoplasm composed of γδ mature T-cells and γδ precursor T-cells with marked eosinophilia that is inapplicable to the current 2016 ...
Samah Kohla, Feryal Ibrahim, Ilham Bilal, Einas Al Kuwari, Ahmad Al-Sabbagh   +4 more
doaj   +1 more source

Pediatric lymphoma may develop by "one-step" cell transformation of a lymphoid cell [PDF]

arXiv, 2018
Lymphomas are a large group of neoplasms developed from lymphoid cells (LCs) in lymph nodes (LNs) or lymphoid tissues (LTs). Some forms of lymphomas, including Burkitt lymphoma (BL), ALK+ anaplastic large cell lymphoma (ALK+-ALCL), and T-cell lymphoblastic lymphoma/leukemia (T-LBL), occur mainly in children and teenagers.
arxiv  

How I Treat Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (T-ALL) and T-cell Lymphoblastic Lymphoma in Children.

Blood, 2019
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that has historically been associated with a very poor prognosis. Nevertheless, despite a lack of incorporation of novel agents, the development of intensified T-ALL focused ...
D. Teachey, D. O’Connor
semanticscholar   +1 more source

Precursor T-Cell Acute Lymphoblastic Leukemia/ Lymphoblastic Lymphoma and Acute Biphenotypic Leukemias [PDF]

, 2007
Xin Han, Carlos E. Bueso‐Ramos
openalex   +2 more sources

A Deep Autoencoder System for Differentiation of Cancer Types Based on DNA Methylation State [PDF]

arXiv, 2018
A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The developed deep learning system uses a CpG island state classification sub-system to complete sets of missing ...
arxiv  

Mandible infiltration as a clinical signal of extramedullary B-cell acute lymphoblastic leukemia/lymphoma in a child: Report of a rare case

Oral Oncology Reports
B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) is a type of malignancy involving uncontrolled proliferation of B-precursor lymphoid cells. This case report delineates B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) manifesting in the mandible and ...
Paulo Victor Mendes Penafort, Lady Paola Aristizabal Arboleda, Sérgio Takashi Kussaba, Izilda Aparecida Cardinalli, Regina Maria Holanda de Mendonça, Márcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos-Silva   +7 more
doaj  

LeukoNet: DCT-based CNN architecture for the classification of normal versus Leukemic blasts in B-ALL Cancer [PDF]

arXiv, 2018
Acute lymphoblastic leukemia (ALL) constitutes approximately 25% of the pediatric cancers. In general, the task of identifying immature leukemic blasts from normal cells under the microscope is challenging because morphologically the images of the two cells appear similar.
arxiv  

Deep Learning Algorithms for Early Diagnosis of Acute Lymphoblastic Leukemia [PDF]

arXiv
Acute lymphoblastic leukemia (ALL) is a form of blood cancer that affects the white blood cells. ALL constitutes approximately 25% of pediatric cancers. Early diagnosis and treatment of ALL are crucial for improving patient outcomes. The task of identifying immature leukemic blasts from normal cells under the microscope can prove challenging, since the
arxiv