Results 101 to 110 of about 59,825 (253)

The experience of relapsed Burkitt lymphoma treatment with targeted drugs and autologous/allogeneic stem cell transplantation

Онкогематология
The use of high-effective, multicomponent, risk-adopted chemoimmunotherapy schemes in children with Burkitt lymphoma reached advanced long-term progression-free survival over 90 % even for high risk patients.
T. T. Valiev, A. A. Khachatryan, S. V. Goryacheva, N. A. Batmanova, K. I. Kirgizov, S. R. Varfolomeeva   +5 more
doaj   +1 more source

Immunophenotypic features of bone marrow tumor cell in Burkitt lymphoma/leukemia: B-lineage acute lymphoblastic leukemia diagnostics opportunities

Онкогематология, 2017
Bone marrow tumor blasts immunophenotyping is an essential part of Burkitt lymphoma/leukemia (BL) and B-cell precursor acute lymphoblastic leukemia (BCP-ALL) differential diagnostics.
I. A. Demina, T. Yu. Verzhbitskaya, S. A. Kashpor, S. A. Plyasunova, M. E. Dubrovina, L. G. Fechina, N. V. Myakova, E. V. Samochatova, A. A. Maschan, A. M. Popov   +9 more
doaj   +1 more source

Use of the osmolal gap in diagnosing mixed physiology hyponatremia in a child with B‐cell acute lymphoblastic leukemia

Clinical Case Reports, 2023
Key Clinical Message Hyponatremia is common among children undergoing treatment for hematologic malignancies and may be attributed to multiple underlying causes.
Jonathan M. Gabbay, Andrew E. Place, Maya Ilowite, Jia Zhu   +3 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol [PDF]

, 2015
DNA copy number analysis has been instrumental for the identification of genetic alterations in B-cell precursor acute lymphoblastic leukemia. Notably, some of these genetic defects have been associated with poor treatment outcome and might be relevant ...
Bakkus, Marleen, Benoît, Yves, Bertrand, Yves, Cavé, Hélène, Caye, Aurélie, Clappier, Emmanuelle, Costa, Vitor, De Moerloose, Barbara, Ferster, Alina, Ghazavi, Farzaneh, Grarde, Nathalie, Helsmoortel, Hetty, Lammens, Tim, Mazingue, Françoise, Meul, Magali, Minckes, Odile, Philippé, Jan, Plat, Geneviève, Plouvier, Emmanuel, Poirée, Marilyne, Speleman, Frank, Suciu, Stefan, Uyttebroeck, Anne, van der Werff Ten Bosch, Jutte, Van Roy, Nadine, Van Vlierberghe, Pieter, Yakouben, Karima, Zegrari, Samira   +27 more
core   +3 more sources

Faecalibaculum rodentium Alleviates Ionizing Radiation‐Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu, Hui Guo, Na Sun, Rui Xiao, Binbin Ji, Ruihan Jiang, Fuxing Dong, Chen Yao, Xuerong Wang, Rongqing Li, Jie Zhao, Xueqin Li, Shengzhe Gong, Yongqin Qin, Xin Chen, Yuchen Pan, Takayuki Ikezoe, Jing Yang   +17 more
wiley   +1 more source

Tumor necrosis factor-alpha regulates the expression of inducible costimulator receptor ligand on CD34+ progenitor cells during differentiation into antigen presenting cells [PDF]

, 2001
The inducible costimulator receptor (ICOS) is a third member of the CD28 receptor family that regulates T cell activation and function. ICOS binds to a newly identified ligand on antigen presenting cells different from the CD152 ligands CD80 and CD86. We
Aicher, A, Clark, EA, Daemen, K, Hayden-Ledbetter, M, Irgang, M, Korner, I, Ledbetter, JA, Pezzutto, A, Richter, G, Westermann, J   +9 more
core  

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou, Zhenfei Zhong, Peng Hu, Weigang Wang, Ying Song, Na Yang, Fangyan He, Yajie Li, Qi Sa, Yanmei Yang, Qinmiao Sun, Tonghua Yang, Beibei Zhang, Dahua Chen   +13 more
wiley   +1 more source

T-cell lymphoblastic lymphoma and leukemia: different diseases from a common premalignant progenitor?

Blood Advances, 2020
T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) represent malignancies that arise from the transformation of immature precursor T cells.
E. Kroeze, J. Loeffen, V. M. Poort, J. Meijerink   +3 more
semanticscholar   +1 more source

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia [PDF]

, 2016
Increasing knowledge concerning the biology of hematologic malignancies as well as the role of the immune system in the control of these diseases has led to the development and approval of immunotherapies that are resulting in impressive clinical ...
Abonour, Rafat, Anderson, Kenneth C., Ansell, Stephen M., Avigan, David, Barbarotta, Lisa, Barrett, Austin John, Bergsagel, Leif, Bishop, Michael R., Borrello, Ivan, Boyiadzis, Michael, Brody, Joshua, Brufsky, Jill, Cairo, Mitchell, Chari, Ajai, Cohen, Adam, Cortes, Jorge, de Lima, Marcos, Dhodapkar, Madhav V., Forman, Stephen J., Friedberg, Jonathan W., Fuchs, Ephraim J., Gore, Steven D., Jagannath, Sundar, Kahl, Brad S, Kline, Justin, Kochenderfer, James N., Kwak, Larry W., Levy, Ronald, Litzow, Mark R., Mahindra, Anuj, Miller, Jeffrey, Munshi, Nikhil C., Orlowski, Robert Z., Pagel, John M., Porter, David L., Russell, Stephen J., Schwartz, Karl, Shipp, Margaret A., Siegel, David, Stone, Richard M., Tallman, Martin S., Timmerman, John M., Van Besien, Koen, Van Rhee, Frits, Waller, Edmund K., Welsh, Ann, Werner, Michael, Wiernik, Peter H.   +47 more
core   +2 more sources