Results 71 to 80 of about 59,825 (253)

Mandible infiltration as a clinical signal of extramedullary B-cell acute lymphoblastic leukemia/lymphoma in a child: Report of a rare case

Oral Oncology Reports
B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) is a type of malignancy involving uncontrolled proliferation of B-precursor lymphoid cells. This case report delineates B-cell lymphoblastic leukemia/lymphoma (B-ALL/LBL) manifesting in the mandible and ...
Paulo Victor Mendes Penafort, Lady Paola Aristizabal Arboleda, Sérgio Takashi Kussaba, Izilda Aparecida Cardinalli, Regina Maria Holanda de Mendonça, Márcio Ajudarte Lopes, Pablo Agustin Vargas, Alan Roger Santos-Silva   +7 more
doaj   +1 more source

Aberrant synaptophysin expression in classic Hodgkin lymphoma

Diagnostic Pathology, 2022
Background Synaptophysin is an immunohistochemical marker for neuroendocrine differentiation and is widely used in pathologic diagnosis. Its expression in malignant lymphoma has not yet been described.
Soyoung Im, Jeong-A. Kim, Gyeongsin Park, Uiju Cho   +3 more
doaj   +1 more source

Primary Cutaneous T-Cell Lymphoblastic Lymphoma: Case Report and Literature Review

Case Reports in Hematology, 2019
Cutaneous involvement by precursor T-cell lymphoblastic leukemia/lymphoma (T-ALL/LBL) is rare, and almost all cases are seen in association with bone marrow, blood, and/or lymph node involvement.
Sharad Khurana, Manuel Beltran, Liuyan Jiang, Ernesto Ayala, Vivek Roy   +4 more
doaj   +1 more source

Candida on oral cavity of pediatric individuals with ALL and its susceptibility to nystatin and amphotericin B

RGO: Revista Gaúcha de Odontologia, 2019
Objective: The aim of this study was to evaluate the prevalence of Candida colonizationon oral cavity of pediatric individuals with acute lymphocytic leukemia (ALL) and its susceptibility/resistance to nystatin and amphotericin B.
Larissa Cavalcanti MONTEIRO, Isabella Lima Arrais RIBEIRO, Roberta Ferreti Bonan Dantas BATISTA, Panmella Pereira MACIEL, Ana Maria Gondim VALENÇA, Ana Carolina Bernardes DULGHEROFF4 , Joelma Rodrigues SOUZA, Yuri Wanderley CAVALCANTI1 , Lucio Roberto Cançado CASTELLANO, Paulo Rogério Ferreti BONAN   +9 more
doaj   +1 more source

Residential exposure to solar ultraviolet radiation and incidence of childhood hematological malignancies in France [PDF]

, 2015
Few studies have investigated the relationship between solar ultraviolet radiation (UV) and childhood hematological malignancies (CHM). This study addresses the associations between residential UV exposure at diagnosis and the incidence of types and ...
Boniol, Mathieu, Clavel, Jacqueline, Coste, Astrid, Doré, Jean-François, Faure, Laure, Goujon, Stéphanie, Hémon, Denis, Marquant, Fabienne   +7 more
core   +3 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms [PDF]

, 2011
Background: Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities,
Agirre, Xabier, Alvarez, Sara, Ammerpohl, Ole, Bibikova, Marina, Brüggemann, Monika, Bug, Stefanie, Calasanz, Maria J., Cruz Cigudosa, Juan, Deckert, Martina, Dreyling, Martin, Du, Ming Q., Dyer, Martin J. S., Dürig, Jan, Fan, Jian-Bing, Gesk, Stefan, Haferlach, Claudia, Hansmann, Martin-Leo, Harder, Lana, Hartmann, Sylvia, Klapper, Wolfram, Küppers, Ralf, Martin-Subero, Jose Ignacio, Montesinos-Rongen, Manuel, Nagel, Inga, Pott, Christiane, Prosper, Felipe, Richter, Julia, Román-Gómez, José, Seifert, Marc, Siebert, Reiner, Stein, Harald, Suela, Javier, Trümper, Lorenz, Vater, Inga, Wickham-Garcia, Eliza   +34 more
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Role of enhancer of zeste homolog 2 polycomb protein and its significance in tumor progression and cell differentiation [PDF]

, 2013
Epigenetics is a branch of genetics that focuses on the heritable changes of DNA or associated proteins, other than DNA sequence variations, which carry information content during cell division [1,2].
Bagella, Luigi Marco, Marchesi, Irene
core   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source