Results 111 to 120 of about 58,276 (219)

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

The development of innate lymphoid cells. [PDF]

Nat Immunol
Das A, Ding Y, Harly C, Bhandoola A.
europepmc   +1 more source

Deregulation of FOXF1/FENDRR from t(14;16)(q32;q24) defines a subtype of high-risk lineage ambiguous leukemia. [PDF]

Blood
Di Giacomo D, Pölönen P, Bardelli V, Kimura S, Pierini V, Pagliaro L, Arniani S, Chang Y, Gao Q, Montefiori LE, Wu Y, Park CS, Wright WC, Vento F, Wei H, Matteucci C, Lei S, Rosikiewicz W, Nardelli C, Lema Fernandez AG, Østergaard A, Backhaus Wagner EA, Baviskar P, Cerrano M, Leocin M, Manabe A, Hirabayashi S, Takita J, Hasegawa D, Miyamoto S, Macchiarulo A, Xu J, Teachey DT, Roti G, Iacobucci I, La Starza R, Mecucci C, Mullighan CG.   +37 more
europepmc   +1 more source

Assessment of the Performance of Siemens Scopio Digital Morphology on Bone Marrow Aspirates in Onco‐Hematology

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Objectives Digital morphology (DM) systems assisted by artificial intelligence are increasingly being introduced into hematology laboratories; however, data on their performance in routine clinical practice for bone marrow aspirates (BMA) remain limited.
Gina Zini, John Marra, Elena Rossi, Silvia Bellesi, Nicoletta Pelliccioni, Giuseppe d'Onofrio, Patrizia Chiusolo   +6 more
wiley   +1 more source

Persistent <i>BCR::ABL1</i>-positive preleukemic stem cells drive late clonal evolution in Philadelphia chromosome-positive ALL. [PDF]

Hemasphere
Martin JE, Cliquot J, Kim R, Mathis S, Cayuela JM, Passet M, Gaillard B, Himberlin C, Baruchel A, Itzykson R, Soulier J, Boissel N, Raffoux E, Cornillet-Lefebvre P, Clappier E.   +14 more
europepmc   +1 more source

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley   +1 more source

The T Cell Receptor: Molecular Sensor, Therapeutic Mediator and Probabilistic Driver of Adaptive Immunity. [PDF]

Immunol Rev
Schober K.
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Erythropoietin exposure disrupts B cell development and drives the emergence of myeloid-biased biphenotypic progenitors. [PDF]

Stem Cell Reports
Chiron-Margerie A, Bessoles S, Sarrabayrouse G, Alhaj-Hussen K, Joulain C, Darde T, de la Grange P, Abina AM, Canque B, Krzysiek R, Hacein-Bey-Abina S.   +10 more
europepmc   +1 more source

Myo1g Mediates NKR‐P1C Expression in Primary Mouse NK Cells and Participates in Cytotoxicity

Immunology, EarlyView.
In this study we analysed the participation of Myosin 1g in the development and functions of murine natural killer (NK) cells; we found that Myosin 1g is expressed in murine‐activated primary NK cells from the spleen. Additionally, in the absence of Myosin 1g, correlates with a reduced expression of NKR‐P1C but not of CD49b or NKp46.
Héctor Romero‐Ramírez, Vania Aminta Zuleica López‐Esparza, Mariana Flores‐Castelán, Leopoldo Santos‐Argumedo   +3 more
wiley   +1 more source