Co-option of lineage plasticity as a hallmark of multipotent acute leukemias. [PDF]
Gutierrez A, Kentsis A.
europepmc +1 more source
ABSTRACT Glutamine (Gln) and glutamic acid (Glu) are the most abundant free amino acids (AAs) in the fish body. Although classified as non‐essential AAs, their supplementation can be a strategy to optimize the growth performance and health of fish.
Cristiana Leonor da Silva Carneiro +9 more
wiley +1 more source
Advanced Lymphoblastic Lymphoma, NOS in Leukaemic Phase Presenting With Sudden and Fatal CNS Haemorrhage. [PDF]
Antiri EK, Gyasi RK, Ulzen-Appiah K.
europepmc +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
S1P in Tumor Microenvironment and Modulation of Anti-Tumor-Directed T-Cell Responses. [PDF]
António PA +5 more
europepmc +1 more source
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Stem-like T cells in cancer immunotherapy: biology, regulation and therapeutic targeting. [PDF]
Wang H +5 more
europepmc +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Myeloid/lymphoid neoplasm with FLT3 gene fusion: report of a case with a novel t(5;13)(q13;q12) SSBP2::FLT3 fusion. [PDF]
Cook JR +6 more
europepmc +1 more source
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source

