Results 41 to 50 of about 50,528 (188)

Primary Cutaneous T-Cell Lymphoblastic Lymphoma: Case Report and Literature Review

Case Reports in Hematology, 2019
Cutaneous involvement by precursor T-cell lymphoblastic leukemia/lymphoma (T-ALL/LBL) is rare, and almost all cases are seen in association with bone marrow, blood, and/or lymph node involvement.
Sharad Khurana, Manuel Beltran, Liuyan Jiang, Ernesto Ayala, Vivek Roy   +4 more
doaj   +1 more source

Natural Killer Cell Lymphoblastic Leukemia/Lymphoma

Definitions, 2020
A provisional entity describing precursor lymphoid neoplasms that express CD56 and immature T-cell markers, lack B-lymphoid and myeloid markers, and have the immunoglobulin and T-cell receptor genes in the germline configuration.

semanticscholar   +1 more source

Myeloid/lymphoid neoplasm with eosinophilia and BCR/FGFR1 rearrangement with transformation to cortical T-lymphoblastic lymphoma and erythroid precursors: a case report

Journal of Medical Case Reports, 2023
Background Myeloproliferative neoplasms are a group of diseases with diverse biological and clinical characteristics. As a provisional separate entity, myeloid/lymphoid neoplasms with eosinophilia and genetic rearrangement have been described, which may ...
Alejandro Pineda Isaza, Santiago Castaño Quintero, Lisceth Paola Quintero González, Fabián Emiliano Ahumada Córdoba, Andrés Felipe Arbeláez Olivar, Juan Carlos Bravo Ocaña   +5 more
doaj   +1 more source

CAR T-cell therapy-transforming treatment of hematological malignancies

Asian Journal of Medical Sciences, 2023
Hematological malignancies are a significant cause of mortality and morbidity in all age groups. According to the Global Burden of Disease Cancer Collaboration, there were about one million incident cases of hematological malignancies worldwide in 2016 ...
Shah Newaz Ahmed , Arun Kumar
doaj   +1 more source

Chimeric Antigen Receptor Based Cellular Therapy for Treatment Of T-Cell Malignancies

Frontiers in Oncology, 2022
T-cell malignancies can be divided into precursor (T-acute lymphoblastic leukemia/lymphoblastic lymphoma, T-ALL/LBL) and mature T-cell neoplasms, which are comprised of 28 different entities.
Kamila Polgárová, Kamila Polgárová, Pavel Otáhal, Cyril Šálek, Cyril Šálek, Robert Pytlík, Robert Pytlík   +6 more
doaj   +1 more source

Additional file 1 of Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma

, 2022
Additional file 1 : Supplementary Figure 1. Flow cytometry analysis on the anti-CD7 CAR T-cells. Supplementary Figure 2. Cytotoxicity analysis of the anti-CD7 CAR T-cells. Supplementary Figure 3. Timeline of treatments and responses. Supplementary Figure 4. T-cell fractions in the PB post CAR T-cells infusion. Supplementary Table 1.
Dai, Hai-ping, Cui, Wei, Cui, Qing-ya, Zhu, Wen-juan, Meng, Hui-min, Zhu, Min-qing, Zhu, Xia-ming, Yang, Lin, Wu, De-pei, Tang, Xiao-wen   +9 more
openaire   +1 more source

Immunotherapy of Acute Lymphoblastic Leukemia and Lymphoma With T Cell–Redirected Bispecific Antibodies

Journal of Clinical Oncology, 2021
The outcome of B-cell precursor acute lymphoblastic leukemia (ALL) is different in children and adults, with overall survival (OS) rates at 5 years ranging from 90% to 45%. Significant needs also remain unmet in patients with B-cell non-Hodgkin lymphoma (
F. Lussana, G. Gritti, A. Rambaldi
semanticscholar   +1 more source

Rapid Progression of Mediastinal Tumor within a Few Days: A Case Report of T Cell Lymphoblastic Lymphoma

대한영상의학회지, 2016
T-cell lymphoblastic lymphoma is a highly aggressive tumor derived from lymphocyte of the thymus, which accounts for 2% of non-Hodgkin's lymphoma. The disease occurs most commonly in adolescent and young adult males.
Tae Ran Ahn, Young Kyung Lee, Hyun Jung Jun, Eun Ah Jung, Jin Sung Son   +4 more
doaj   +1 more source

γδ T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature γδ T-Cell Malignancies

Case Reports in Hematology, 2017
Gamma delta (γδ) T-cell antigen receptor (TCR) expression and its related T-cell differentiation are not commonly reported in T-cell acute lymphoblastic leukemia/lymphoma (T-ALL).
Eric X. Wei, Vasiliki Leventaki, John K. Choi, Susana C. Raimondi, Elizabeth M. Azzato, Sheila A. Shurtleff, Menchu G. Ong, Diana M. Veillon, James D. Cotelingam, Rodney E. Shackelford   +9 more
doaj   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source