Results 191 to 200 of about 21,333 (239)
Highly Secure In Vivo DNA Data Storage Driven by Genomic Dynamics
Advanced Science, EarlyView.Integrated computational‐biological programming enables secure in vivo data storage by generating code tables from either genomes or gene regulatory networks, expanding the encryption key space by over 100 orders of magnitude. Storing code tables within synthetic genes, genomes, or gene regulatory networks adds an additional layer of security by ...
Jiaxin Xu +9 more
wiley +1 more source
Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation
Advanced Science, EarlyView.A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun +8 more
wiley +1 more source
Advanced Science, EarlyView.This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu +14 more
wiley +1 more source
S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning
Advanced Science, EarlyView.Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu +6 more
wiley +1 more source
Advanced Science, EarlyView.An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao +11 more
wiley +1 more source
Advanced Science, EarlyView.The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li +10 more
wiley +1 more source
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Scottish Journal of Theology, 1953
The classical discussion of the doctrine of Predestination and the problem of Free-will is still to be found in Luther's book, the Bondage of the Will. In the course of four hundred pages he ranges through profound Biblical exegesis, trenchant theological statement, narrow scholastic argument, virulent vituperation—developing, through it all, the most ...
openaire +1 more source
The classical discussion of the doctrine of Predestination and the problem of Free-will is still to be found in Luther's book, the Bondage of the Will. In the course of four hundred pages he ranges through profound Biblical exegesis, trenchant theological statement, narrow scholastic argument, virulent vituperation—developing, through it all, the most ...
openaire +1 more source
2018
Predestination appears to be a religious or theological version of universal determinism, a version in which the final determining factor is the will or action of God. It is most often associated with the theological tradition of Calvinism, although some theologians outside the Calvinist tradition, or prior to it (for example, Augustine and Thomas ...
openaire +1 more source
Predestination appears to be a religious or theological version of universal determinism, a version in which the final determining factor is the will or action of God. It is most often associated with the theological tradition of Calvinism, although some theologians outside the Calvinist tradition, or prior to it (for example, Augustine and Thomas ...
openaire +1 more source