Results 141 to 150 of about 105,968 (369)

Pediatric Obesity: Influence on Drug Dosing and Therapeutics [PDF]

open access: yes, 2018
Obesity is an ongoing global health concern and has only recently been recognized as a chronic disease of energy homeostasis and fuel partitioning. Obesity afflicts 17% of US children and adolescents.
Ameer, Barbara, PharmD, MBA, BCPS, FCP   +1 more
core   +1 more source

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt   +12 more
wiley   +1 more source

Metformin attenuates metabolic insulin sensitivity and insulin‐stimulated carbohydrate oxidation after high‐intensity exercise training in adults at risk for metabolic syndrome

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mixed evidence exists on whether metformin adds to or attenuates the insulin‐sensitising effects of exercise. To date, no studies have tested whether metformin differentially impacts exercise training intensity–mediated insulin sensitivity.
Steven K. Malin   +7 more
wiley   +1 more source

Characteristics and risk factors associated with developing prediabetes in Saudi Arabia

open access: yesAnnals of Medicine
Objective Prediabetes is prevalent in Saudi Arabia and globally. It is associated with adverse health outcomes and complications. Consequently, this study aimed to determine the risk factors associated with developing prediabetes in Saudi Arabia.Methods ...
Ayla M. Tourkmani   +7 more
doaj   +1 more source

Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. [PDF]

open access: yes, 2016
Type 1 diabetes (T1D) is caused by autoreactive T cells that recognize pancreatic islet antigens and destroy insulin-producing β-cells. This attack results from a breakdown in tolerance for self-antigens, which is controlled by ectopic antigen expression
Butte, Atul J   +9 more
core   +1 more source

Prevalence of new‐onset diabetes following COVID‐19 infection: A systematic review and meta‐analysis

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim To estimate the prevalence of new‐onset diabetes in adults (≥ 18 years) following SARS‐CoV‐2 infection. Materials and Methods This meta‐analysis includes studies written in English that measured the number of adults (≥ 18 years) diagnosed with diabetes following SARS‐CoV‐2 infection.
Jordan N. Keels   +3 more
wiley   +1 more source

Reasons for patient reluctance to take preventive medications for migraine: Results of the OVERCOME (US) study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This study was undertaken to evaluate patient reasons for nonadoption of migraine‐preventive medications. Despite clear recommendations and eligibility criteria for migraine‐preventive treatment by the American Headache Society and the availability of these treatments, many people with migraine are not taking appropriate ...
Jessica Ailani   +9 more
wiley   +1 more source

Optimal Hemoglobin A1c Levels for Screening of Diabetes and Prediabetes in the Japanese Population

open access: yesJournal of Diabetes Research, 2015
The aim of this study was to evaluate the utility of hemoglobin A1c (HbA1c) to identify individuals with diabetes and prediabetes in the Japanese population. A total of 1372 individuals without known diabetes were selected for this study.
Masanori Shimodaira   +3 more
doaj   +1 more source

Liraglutide inhibits the progression of prediabetes in rats by reducing Raf-1 kinase inhibitor protein [PDF]

open access: diamond, 2021
Fei Gao   +7 more
openalex   +1 more source

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