Results 301 to 310 of about 105,968 (369)

Improved health‐related quality of life with tirzepatide versus semaglutide in adults with obesity or overweight from the SURMOUNT‐5 trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 452-462, January 2026.
Abstract Aims In SURMOUNT‐5, tirzepatide led to greater body weight (BW) reduction versus semaglutide in adults with obesity without T2D. Health‐related quality of life (HRQoL) with tirzepatide versus semaglutide in SURMOUNT‐5 was evaluated. Materials and Methods This analysis included on‐treatment data from participants who received ≥1 dose of ...
Alpana P. Shukla, Julia P. Dunn, Elisa Gomez Valderas, Julia Fraseur Brumm, Chrisanthi A. Karanikas, Theresa Hunter Gibble   +5 more
wiley   +1 more source

Progressive increases in adiposity and ectopic fat surrogates across glycaemic states highlight weight reduction as a key target for type 2 diabetes prevention, especially in younger people

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 654-662, January 2026.
Abstract Aims To determine whether there are progressive changes in weight and ectopic fat surrogates in individuals comparing normoglycaemia, prediabetes and undiagnosed type 2 diabetes, and whether these increments differ by age. Materials and Methods Cross‐sectional analysis of UK Biobank White participants without baseline cardiovascular disease or
Sabrina Scilletta, Paul Welsh, Antonino Di Pino, Naveed Sattar   +3 more
wiley   +1 more source

Paradoxical mortality benefit but increased procedural and ischemic risk in prediabetic chronic total occlusion: a national inpatient sample study. [PDF]

BMC Cardiovasc Disord
Li A, Mondal A, Balogun AS, Patel PV, Kaulback KW, Farmer A, Lin Z.   +6 more
europepmc   +1 more source

Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
This study uncovered sex‐specific metabolic and lipidomic signatures of prediabetes. In PREVADIAB2 (n = 953), clustering by insulin traits revealed four phenotypes. Lipidomics showed women enriched in dihydroceramides and sphingomyelins, while men displayed a higher ceramide/sphingomyelin ratio. These sex‐metabolic phenotypes expose distinct lipidomes,
Ana F. Pina, Maria João Meneses, Fabrizia Carli, Rogério T. Ribeiro, Luís Gardete‐Correia, José M. Boavida, João F. Raposo, Amalia Gastaldelli, M. Paula Macedo   +8 more
wiley   +1 more source

Addressing gaps in pre-diabetes care: health professionals' knowledge, attitudes, and counseling practices. [PDF]

BMC Res Notes
Shafique K, Shah N, Mughal S, Ansari I, Siddiqui R, Uddin MF, Khan RA, Niazi AK, Naz S.   +8 more
europepmc   +1 more source

Amyloid‐beta (1–40) peptide is associated with systemic metabolic health

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Plasma amyloid‐beta 1–40 (Aβ40) levels were measured in 449 individuals without overt cardiovascular disease. Higher Aβ40 was independently associated with metabolic syndrome, dyslipidemia (low HDL‐C, high triglycerides), insulin resistance (TyG index), diabetes mellitus and increased BARD score indicating liver fibrosis risk.
Kateryna Sopova, Dimitrios Delialis, Evmorfia Aivalioti, Georgios Georgiopoulos, Stravros Athanasopoulos, Georgios Zervas, Christina Konstantaki, Marco Sachse, Martin Sigl, Daniel Duerschmied, Simon Tual‐Chalot, Kimon Stamatelopoulos, Konstantinos Stellos   +12 more
wiley   +1 more source

Prediabetes Subgroups, Type 2 Diabetes Risk, and Differential Effects of Preventive Interventions.

J Clin Endocrinol Metab
Stafford JM, Casanova R, Jaeger BC, Demesie Y, Wells BJ, Bancks MP.   +5 more
europepmc   +1 more source

The Association of Central Corneal Thickness and Central Corneal Epithelial Thickness with Anthropometric and Biochemical Parameters in Subjects with Impaired Glucose Metabolism. [PDF]

Diagnostics (Basel)
Boyacı İ, Demirci G.
europepmc   +1 more source

Multiparameter MRI assessment of metformin and exercise effects on skeletal muscle in prediabetes: a randomized controlled trial. [PDF]

Eur Radiol Exp
Yu F, Dong Y, Ye N, Xing C, Lyu X, Chen Y, Yang X, Pan S.   +7 more
europepmc   +1 more source

BMI Percentile Cutoffs for Overweight and Obesity Are Set Too High in Terms of Adiposity and Metabolic Markers for Asian Children and Adolescents

Pediatric Obesity, Volume 21, Issue 1, January 2026.
ABSTRACT Objectives Asian adults develop metabolic complications at lower body mass indices (BMIs) compared with other ethnic groups, leading to lower BMI cutoffs for overweight and obesity. However, it remains unclear whether such adjustments are warranted in Asian children and adolescents.
Suk‐Jin Hong, Xinlian Zhang, Phillipp Hartmann   +2 more
wiley   +1 more source