Results 11 to 20 of about 28,969 (227)

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Amyloid beta and diabetic pathology cooperatively stimulate cytokine expression in an Alzheimer's mouse model [PDF]

open access: yes, 2020
Background Diabetes is a risk factor for developing Alzheimer's disease (AD); however, the mechanism by which diabetes can promote AD pathology remains unknown.
Fernández Ponce, Cecilia Matilde   +7 more
core   +3 more sources

The natural history of periodontal disease: The Java study—Origin, implementation, and results 35 years on

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract This review describes the origin and results of the prospective longitudinal study to test potential prognostic indicators for periodontal breakdown in a population deprived of regular dental care. Experimental gingivitis studies in individuals highly susceptible or highly resistant to periodontitis showed that bleeding on probing developed ...
Ubele Van der Velden
wiley   +1 more source

Hemoglobin A1c Levels Modify Associations between Dietary Acid Load and Breast Cancer Recurrence. [PDF]

open access: yes, 2020
BackgroundMetabolic acidosis promotes cancer metastasis. No prospective studies have examined the association between dietary acid load and breast cancer recurrence among breast cancer survivors, who are susceptible to metabolic acidosis.
Hsu, Fang-Chi   +4 more
core   +2 more sources

Association of metabolic dysregulation with volumetric brain magnetic resonance imaging and cognitive markers of subclinical brain aging in middle-aged adults: the Framingham Offspring Study. [PDF]

open access: yes, 2011
ObjectiveDiabetic and prediabtic states, including insulin resistance, fasting hyperglycemia, and hyperinsulinemia, are associated with metabolic dysregulation.
Au, Rhoda   +9 more
core   +5 more sources

Oxidative Stress, DNA Damage and Serum Vitamin D Levels in Prediabetes [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: Prediabetes or intermediate hyperglycaemia is a high risk condition with blood glucose levels higher than the normal glycaemic values but lower than the Diabetes Mellitus (DM) diagnostic value.
Ajay Chauhan   +4 more
doaj   +1 more source

Characterization of the Prediabetic State [PDF]

open access: yesAmerican Journal of Hypertension, 1997
First degree relatives of patients with non-insulin-dependent diabetes mellitus (NIDDM) have a 40% risk of developing NIDDM during their lifetime and the risk seems to be greater if the disease is inherited from the mother than from the father. It has also become clear that metabolic abnormalities are demonstrable long before the disease becomes ...
L, Groop, C, Forsblom, M, Lehtovirta
openaire   +2 more sources

Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2020
Background. Prediabetes is an intermediary hyperglycaemic state that precedes type 2 diabetes mellitus (T2DM) in which abnormal metabolism of glucose and lipids occurs in organs such as the liver.
Akinjide Moses Akinnuga   +5 more
doaj   +1 more source

Elevated cystatin-C concentration is associated with progression to prediabetes: the Western New York Study [PDF]

open access: yes, 2007
OBJECTIVE – We conducted a nested case-control investigation to examine if elevated baseline concentrations of cystatin-C predicted progression from normoglycaemia to prediabetes over 6 years of follow-up from the Western New York Health Study. RESEARCH
Dmochowski, Jacek   +5 more
core   +1 more source

Plasma Adiponectin Levels in Elderly Patients with Prediabetes [PDF]

open access: yesEndocrinology and Metabolism, 2015
BackgroundThe significance of adiponectin levels in elderly individuals with prediabetes has yet to be determined. Thus, the present study was performed to evaluate the relationships between adiponectin levels and anthropometric variables, body ...
Si Eun Kong   +5 more
doaj   +1 more source

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