Background: Seven landmark randomised controlled trials, with some that began as early as the 1990s, observed the prediabetic state, namely, impaired glucose tolerance and impaired fasting glucose conditions, against the impact of lifestyle interventions
Joseph Edwards, Hassan Hosseinzadeh
doaj +1 more source
Background Lipid abnormality pervasively is associated with the risk of type 2 diabetes mellitus. To the best of our knowledge, there is no study that has examined the longitudinal changes in a wide range of serum lipid profiles in prediabetic subjects ...
Shahla Safari +3 more
doaj +1 more source
Consistency of compact and extended models of glucose-insulin homeostasis: The role of variable pancreatic reserve [PDF]
Published compact and extended models of the glucose-insulin physiologic control system are compared, in order to understand why a specific functional form of the compact model proved to be necessary for a satisfactory representation of acute ...
De Gaetano, Andrea +2 more
core +1 more source
Value of serum 1,5-anhydroglucitol measurements in childhood obesity in the continuum of diabetes [PDF]
PurposeThe prevalence of type 2 diabetes mellitus (T2DM) and obesity are currently increasing. Accordingly, the concept of "preventing diabetes" in high-risk groups has become more important in diabetic care, but the use of glycated hemoglobin (HbA1c) as
Ha Yeong Yoo +4 more
doaj +1 more source
Skin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes [PDF]
Aims<br/> Microvascular dysfunction occurs in Type 2 diabetes and in subjects with fasting hyperglycaemia. It is unclear whether this dysfunction relates to dysglycaemia.
A. C. Shore +26 more
core +1 more source
TyG index and insulin resistance in beta-thalassemia [PDF]
Insulin resistance (IR) underlies some glucose metabolism abnormalities in thalassemia major. Recently, triglyceride glucose index (TyG) has been proposed for evaluating insulin resistance as a simple, low cost, and accessible tool.
Fayaz, M. +3 more
core +1 more source
Alendronate improves fasting plasma glucose and insulin sensitivity and decreases insulin resistance in prediabetic osteopenic postmenopausal women: a randomized triple-blind clinical trial [PDF]
Aims Postmenopausal women receive bisphosphonates for osteoporosis treatment. The effect of these medications on developing diabetes mellitus (DM) in prediabetic patients is yet to be investigated.
Amini, Massoud +8 more
core +2 more sources
Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark
Background Recent studies have indicated an association of gut microbiota and microbial metabolites with type 2 diabetes mellitus (T2D). However, large-scale investigation of the gut microbiota of “prediabetic” (PD) subjects has not been reported ...
Nishal Kumar Pinna +25 more
doaj +1 more source
Background: Training programs must be evaluated to understand whether the training was successful at enabling staff to implement a program with fidelity. This is especially important when the training has been translated to a new context. The aim of this
Tineke E. Dineen +4 more
doaj +1 more source
Impaired Insulin Profiles Following a Single Night of Sleep Restriction: The Impact of Acute Sprint Interval Exercise [PDF]
Experimental sleep restriction (SR) has demonstrated reduced insulin sensitivity in healthy individuals. Exercise is well-known to be beneficial for metabolic health.
Ellis, Jason +5 more
core +2 more sources

