Results 81 to 90 of about 28,969 (227)

Poly(2-propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation. [PDF]

, 2017
Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner.
Bracho-Sanchez, Evelyn, Carstens, Matthew R, Duvall, Craig L, Fernando, Lawrence P, Keselowsky, Benjamin G, Lewis, Jamal S, Yang, Lirong   +6 more
core   +1 more source

Exercise‐induced miR‐126 expression improves vascular health in prediabetes: A randomized controlled trial

Experimental Physiology, EarlyView.
Abstract In this study, we investigated whether a structured aerobic exercise programme could enhance microRNA‐126 (miR‐126) expression and improve subclinical atherosclerosis markers [carotid intima–media thickness (CIMT) and ankle–brachial index (ABI)] in individuals with prediabetes.
Elif Yildirim Ayaz, Sadrettin Pençe, Sibel Kuraş, Emine Şeyma Denli Yalvaç, Banu Mesci, Özden Ezgi Üner, Fatoş Nimet Kaya, Berna Dincer, Ferruh Kemal Işman, Aytekin Oğuz   +9 more
wiley   +1 more source

How will the Internet of Things enable Augmented Personalized Health?

, 2017
Internet-of-Things (IoT) is profoundly redefining the way we create, consume, and share information. Health aficionados and citizens are increasingly using IoT technologies to track their sleep, food intake, activity, vital body signals, and other ...
Jaimini, Utkarshani, Sheth, Amit, Yip, Hong Yung   +2 more
core   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Lower glycemic status was associated with pancreatic cancer risk in prediabetes, but not in diabetes: A nationwide cohort study

Journal of Diabetes Investigation
Introduction Hyperglycemia or diabetes mellitus (DM) is a well‐known risk factor for pancreatic cancer, but it is uncertain whether well‐controlled glycemic status can affect the pancreatic cancer incidence rate.
Dong‐Hoe Koo, Jin‐Hyung Jung, Kyungdo Han, Cheol‐Young Park   +3 more
doaj   +1 more source

Translational studies of chronic supplementation with a mitochondria‐targeted antioxidant to improve physical function with ageing

The Journal of Physiology, EarlyView.
Abstract figure legend Chronic oral supplementation with the mitochondria‐targeted antioxidant MitoQ (4 weeks; 250 µm) mitigates age‐related physical dysfunction in old mice, which is associated with reductions in skeletal muscle mitochondria‐specific superoxide and markers of mitochondrial reactive oxygen species (mitoROS)‐related oxidative stress and
Kevin O. Murray, Rachel A. Gioscia‐Ryan, Jaime N. Justice, Jessica R. Santos‐Parker, Nina Z. Bispham, David A. Hutton, Sanna Darvish, Jill Miyamoto‐Ditmon, Zachary S. Clayton, Michel Chonchol, Douglas R. Seals, Matthew J. Rossman   +11 more
wiley   +1 more source

Effects of Lifestyle Modification and Anti-diabetic Medicine on Prediabetes Progress: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2019
Background: Pre-diabetes is a risk factor for full-blown diabetes; it presents opportunities to prevent the actual diseases. It is therefore essential to identify effective preventive strategies, and to clarify the direction of future research.Methods ...
Zhi Sheng, Jia-Yu Cao, Ying-Chang Pang, Hang-Cheng Xu, Jing-Wen Chen, Jun-Hua Yuan, Rui Wang, Cai-Shun Zhang, Liu-Xin Wang, Jing Dong, Jing Dong   +10 more
doaj   +1 more source

Dietary essential oils modulate post‐mortem oxidative damage in trout fillets exposed to slaughter stress during frozen storage

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3686-3695, April 2026.
Abstract BACKGROUND Slaughter is a critical phase in aquaculture that can severely compromise both animal welfare and product quality. Stress responses triggered during this stage may accelerate post‐mortem biochemical degradation and promote oxidative damage in fish fillets. Essential oils, known for their antioxidant and anti‐inflammatory properties,
Lucía Méndez, Giulia Secci, Lorena Barros, Gabriel Dasilva, Giuliana Parisi, Isabel Medina   +5 more
wiley   +1 more source

Body mass index and health care utilization in diabetic and nondiabetic individuals. [PDF]

, 2015
BackgroundAlthough controversial, most studies examining the relationship of body mass index (BMI) with mortality in diabetes suggest a paradox: the lowest risk category is above normal weight, versus normal weight in nondiabetic persons.
Bertakis, Klea D, Franks, Peter, Jerant, Anthony   +2 more
core   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source