Results 101 to 110 of about 872,279 (317)

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Real-time Prediction of 1H and 13C Chemical Shifts with DFT accuracy using a 3D Graph Neural Network

open access: yes, 2021
The computational prediction of NMR chemical shifts using quantum mechanical calculations is now commonplace in aiding organic structural assignment since spectra can be computed for several candidate structures and then compared with experimental values
Robert, Paton   +4 more
core   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann   +17 more
wiley   +1 more source

Efficiency of Genomic Selection for Developing Superior Pure Lines

open access: yesAgronomy
The objectives were to assess the efficacy of genomic selection in pure line breeding, using a simulated dataset, the significance of several factors, including model updating, selection intensity, early generation (F2) selection, dominance, and the ...
Jean Paulo Aparecido da Silva   +1 more
doaj   +1 more source

Multivariate GBLUP Improves Accuracy of Genomic Selection for Yield and Fruit Weight in Biparental Populations of Vaccinium macrocarpon Ait

open access: yesFrontiers in Plant Science, 2018
The development of high-throughput genotyping has made genome-wide association (GWAS) and genomic selection (GS) applications possible for both model and non-model species.
Giovanny Covarrubias-Pazaran   +9 more
doaj   +1 more source

AGenDA: gene prediction by cross-species sequence comparison

open access: yes, 2004
Taher L, Rinner O, Garg S, Sczyrba A, Morgenstern B. AGenDA: gene prediction by cross-species sequence comparison. Nucleic Acids Research. 2004;32(Web Server):W305-W308.Automatic gene prediction is one of the major challenges in computational sequence ...
Sczyrba, Alexander ; https://orcid.org/   +9 more
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Genomic selection accuracy for the yield trait in alfalfa half-sib families based on GWAS strategies

open access: yesGrass Research
Alfalfa (Medicago sativa L.), a globally vital perennial forage supporting livestock, faces stagnant yield improvement due to polyploid complexity and slow genetic gains.
Yangyang Han   +7 more
doaj   +1 more source

Development and comparison of payment behaviour prediction models for two South African state departments

open access: yesSouth African Journal of Economic and Management Sciences, 2017
Background: No credit rating methodology currently exists for any of South Africa’s sub nationals. Aim: To develop a generic, quantitative credit rating methodology for the Department of Health and the Department of Education combined, as well as ...
Erika Fourie   +2 more
doaj   +1 more source

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