Results 61 to 70 of about 4,436,251 (260)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Use of Deep Learning to Study Modeling Deterioration of Pavements a Case Study in Iowa

open access: yesInfrastructures, 2020
This paper describes the process and outcome of deterioration modeling for three different pavement types (asphalt, concrete, and composite) in the state of Iowa.
Seyed Amirhossein Hosseini   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Efficiency of Genomic Selection for Developing Superior Pure Lines

open access: yesAgronomy
The objectives were to assess the efficacy of genomic selection in pure line breeding, using a simulated dataset, the significance of several factors, including model updating, selection intensity, early generation (F2) selection, dominance, and the ...
Jean Paulo Aparecido da Silva   +1 more
doaj   +1 more source

Genomic Studies Reveal Substantial Dominant Effects and Improved Genomic Predictions in an Open-Pollinated Breeding Population of Eucalyptus pellita

open access: yesG3: Genes, Genomes, Genetics, 2020
Most of the genomic studies in plants and animals have used additive models for studying genetic parameters and prediction accuracies. In this study, we used genomic models with additive and nonadditive effects to analyze the genetic architecture of ...
Saravanan Thavamanikumar   +3 more
doaj   +1 more source

Randomized Trial Comparing Prediction Accuracy of Two Swept Source Optical Coherence Tomography Biometers

open access: yes, 2023
Sam Multack,1 Nellie Plummer,1 Gerard Smits,2 Brad Hall3 1Multack Eye Care, Frankfort, IL, USA; 2CSC, Inc., Santa Barbara, CA, USA; 3Sengi, Penniac, NB, CanadaCorrespondence: Sam Multack, Multack Eye Care, 22200 Wolf Road, Frankfort, IL, 60423, USA, Tel +
Smits G, Multack S, Hall B, Plummer N
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Effect of milk recording scheme on lactation milk yields prediction accuracy

open access: yesMljekarstvo, 2009
Different AT milk recording schemes, with purpose of detection of scheme with the highest lactation milk yields prediction accuracy as well as with simplest practice application, were compared in this study.
Dragomir Kompan   +4 more
doaj  

Genomic selection accuracy for the yield trait in alfalfa half-sib families based on GWAS strategies

open access: yesGrass Research
Alfalfa (Medicago sativa L.), a globally vital perennial forage supporting livestock, faces stagnant yield improvement due to polyploid complexity and slow genetic gains.
Yangyang Han   +7 more
doaj   +1 more source

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