Results 91 to 100 of about 2,497,925 (305)
Supplementary Tables from Network Propagation Predicts Drug Synergy in Cancers
, 2018 This file contains the Supplementary Tables 1-10. These tables contains 1. the values of model stacking weights 2.prediction correlations of cell line, drug, and drug pairs 3. the 85 cancer cell lines and their corresponding tissues 4.
Tingyang Li (14933064) +3 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
PCMDI/cmip6-cmor-tables: update to 01.00.15
, 2017 JSON Tables for CMOR3 to create CMIP6 ...
Javier Vegas-Regidor +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Machine Learning with ApplicationsTabular data support many high-value prediction tasks across science and industry, but their heterogeneous schemas, mixed data types, and variable dataset sizes have made cross-dataset generalization difficult. This review examines the rapid emergence of
Jaume Manero +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Estimation errors in input–output tables and prediction errors in computable general equilibrium analysis [PDF]
We used 1995-2000-2005 linked input-output (IO) tables for Japan to examine estimation errors of updated IO tables and the resulting prediction errors in computable general equilibrium (CGE) analysis developed with updated IO tables.
HOSOE, Nobuhiro
core
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Aplicabilidad de la Predicción de Moyers 75% en pacientes Mapuche-Hulliche, Chile
OdontoestomatologíaObjetivo: determinar aplicabilidad del método Moyers 75% en población mapuche huilliche, Chile. Material y metodos: estudio descriptivo observacional se evaluó la predicción de Moyers nivel 75% en una población Mapuche Huilliche entre los 11 y 17 años de
María Antonieta Pérez +4 more
doaj