Results 71 to 80 of about 1,720,482 (294)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

In-situ remaining useful life prediction of aircraft auxiliary power unit based on quantitative analysis of on-wing sensing data

Advances in Mechanical Engineering, 2020
The in-situ prognostics and health management of aircraft auxiliary power unit faces difficulty using the sparse on-wing sensing data. As the key technology of prognostics and health management, remaining useful life prediction of in-situ aircraft ...
Liansheng Liu, Qing Guo, Lulu Wang, Datong Liu   +3 more
doaj   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

IMPROVING HEART FAILURE UNIT READMISSION PREDICTION

Journal of the American College of Cardiology, 2017
Background: Readmission following an index admission for heart failure (HF) remains the leading cause of hospital readmission in the U.S. Risk prediction tools at the time of hospital discharge (d/c) provide better allocation of resources towards higher-risk populations.
Tom Quisel, Richard Milani, Luca Foschini   +2 more
openaire   +1 more source

Bayesian recursive parameter estimation for hydrologic models [PDF]

, 2001
The uncertainty in a given hydrologic prediction is the compound effect of the parameter, data, and structural uncertainties associated with the underlying model.
Gupta, H, Sorooshian, S, Thiemann, M, Trosset, M   +3 more
core   +1 more source

Anomalous Bloch oscillations in one dimensional parity-breaking periodic potentials

, 2010
We investigate the dynamics of a wave packet in a parity-breaking one-dimensional periodic potential slowly varied in time and perturbed by a linear potential. Parity is broken by considering an asymmetric double well per unit cell.
Modugno, Michele, Pettini, Giulio
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Unequal socioeconomic exposure to drought extremes induced by stratospheric aerosol injection [PDF]

Atmospheric Chemistry and Physics
As global temperature rises, the severity and frequency of droughts are projected to increase. Stratospheric aerosol injection (SAI) has been proposed as a potential solution to reduce surface temperatures, but its effectiveness in alleviating drought ...
W. Fu, X. Yue, C. Tian, R. Xu, Y. Guo
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source