Results 241 to 250 of about 743,383 (345)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

From risk factors to predictive modelling: applying machine learning to childhood malaria surveillance in resource-limited settings. [PDF]

BMC Infect Dis
Ashaolu JO, Akanji TS, Ayansola VI, Olawale-Succes OO, Sunday AJ, Some SYM.   +5 more
europepmc   +1 more source

New unified model for predicting ductile fracture in structural steels

佩雲, 张
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Identifying landmark factors of anal fistulas through predictive modelling for adverse surgical outcomes: a retrospective cohort study. [PDF]

BMC Surg
Liu G, Xu K, Meng Q, Wang J, Li Y.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Association between serum 25-hydroxyvitamin D levels and pulmonary function in elderly patients with chronic kidney disease: correlation analysis and exploratory predictive modelling. [PDF]

Front Endocrinol (Lausanne)
Dai X, Zhou M, Gao Q, Yuan L, Jiang X, Li J, Zhang L, Guo C, Gu N.   +8 more
europepmc   +1 more source

Model Averaging in Markov-Switching Models: Predicting National Recessions with Regional Data

, 2017
Pierre Guérin, Danilo LeivaaLeon
openalex   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

AI-driven predictive modelling of orthodontic relapse using retainer compliance and patient factors. [PDF]

Bioinformation
S Agrawal M, Chawla R, Khan SA, Pandiyath DB, Das S, Marwaha J.   +5 more
europepmc   +1 more source