Results 131 to 140 of about 1,068,736 (293)

Perception as self-organizing interaction: embodied cognition, artificial intelligence, and autism

open access: yesFrontiers in Psychology
Perception has traditionally been conceptualized as the internal reconstruction of external stimuli, both in cognitive science and in artificial intelligence (AI).
Gerry Leisman   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Does the brain really know what word is coming next?

open access: yeseLife
Apparent neural encoding of future words may arise from the statistical structure of language itself, rather than from predictive computations in the brain.
Richard J Antonello
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Counter-factual mathematics of counterfactual predictive models

open access: yesFrontiers in Psychology, 2014
Maria Eliza Otworowska   +2 more
doaj   +1 more source

The Temporality of Aberrant Salience and Schizophrenia

open access: yesFrontiers in Integrative Neuroscience, 2022
David H. V. Vogel
doaj   +1 more source

Building Predictive Models in R Using the caret Package [PDF]

open access: yes
The caret package, short for classification and regression training, contains numerous tools for developing predictive models using the rich set of models available in R.
Max Kuhn
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Introducing ActiveInference.jl: A Julia Library for Simulation and Parameter Estimation with Active Inference Models

open access: yesEntropy
We introduce a new software package for the Julia programming language, the library ActiveInference.jl. To make active inference agents with Partially Observable Markov Decision Process (POMDP) generative models available to the growing research ...
Samuel William Nehrer   +5 more
doaj   +1 more source

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