Results 61 to 70 of about 277,874 (307)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Prediction and validation of microRNAs and their targets [PDF]
FEBS Letters, 2005 MicroRNAs are short non‐coding RNAs that inhibit translation of target genes by binding to their mRNAs, and have been shown to play a central role in gene regulation in health and disease. Sophisticated computer‐based prediction approaches of microRNAs and of their targets, and effective biological validation techniques for validating these predictions,
openaire +2 more sources
Predictive validity of tested models.
, 2018 Predictive validity of tested models.
Nicholas Graetz (5626766) +2 more
core +1 more source
Gender prediction in HIGH predictive validity context
, 2020 follow-up pre-registration of "Gender prediction in low predictive validity ...
Elise van Wonderen, Mante S. Nieuwland
core +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The blazar sequence: validity and predictions [PDF]
Astrophysics and Space Science, 2007 The "blazar sequence" posits that the most powerful BL Lacertae objects and flat-spectrum radio quasars should have relatively small synchrotron peak frequencies, nu_peak, and that the least powerful such objects should have the highest nu_peak values.
openaire +2 more sources
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source