Results 81 to 90 of about 797,608 (305)

Development and Validation of a Task-Technology Fit Questionnaire to Evaluate Telemedicine Applications From Physicians’ Perspective

open access: yesIEEE Access
Telemedicine has the potential to enhance both the accessibility and quality of healthcare services. Patients can access telemedicine through various modes, including applications.
Ni Luh Saddhwi Saraswati Adnyani   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Gangs, Guns, and Drugs: Recidivism among Serious, Young Offenders [PDF]

open access: yes, 2007
The primary goal of this study is to understand the factors that best explain recidivism among a sample of 322 young men aged 17 to 24 years released from prison in a Midwestern state.
Adams   +83 more
core   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Social and non-social directional cues differentially orient attention by learned habit

open access: yesFrontiers in Human Neuroscience
IntroductionSince an early age, we are implicitly motivated to use the direction of eye gaze of others to learn about the environment, and we orient our attention in space based on this directional signal.
Claudia Salera   +3 more
doaj   +1 more source

Psychological Test Validity [PDF]

open access: yesСовременная зарубежная психология, 2015
This paper presents a theoretical overview of current aspects about the validity problems of psychological tests. The article demonstrates the importance of the development of psychological tests and the scientific studies of their validity, describes ...
Gessmann H.-W., Sheronov E.A.
doaj  

A test of the predictive validity of non-linear QALY models using time trade-off utilities [PDF]

open access: yes
This paper presents a test of the predictive validity of various classes of QALY models (i.e., linear, power and exponential models). We first estimated TTO utilities for 43 EQ-5D chronic health states and next these states were embedded in health ...
Ildefonso Méndez   +3 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Digital hand‐held arthrometry is a reliable and accurate adjunct for diagnosing acute anterior cruciate ligament tears

open access: yesJournal of Experimental Orthopaedics
Purpose To evaluate the intrarater reliability and predictive validity of Lachmeter® measurements for diagnosing acute anterior cruciate ligament (ACL) tears, and to propose diagnostic thresholds.
Richard Norris   +5 more
doaj   +1 more source

Learning styles inventories: an update of coffield, moseley, hall, & ecclestone`s reliability and validity matrix [PDF]

open access: yes, 2018
Introduction. One of the many notions that have been introduced in education in the last 50 years is that of learning styles. This idea is very popular and enjoys good acceptance.
Leyva-Cruz, María G.   +2 more
core   +2 more sources

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