Results 281 to 290 of about 17,604,202 (410)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Predictive value of HBeAg titer dynamics for HBsAg clearance in pediatric chronic hepatitis B. [PDF]

Front Pediatr
Hong S, Hwang JH, Kim K, Do Y, Kwak N, Suh HR, Choi S, Kang B, Choe BH.   +8 more
europepmc   +1 more source

Predictive Value of Clinical Features in Diagnosing Obstructive Sleep Apnea [PDF]

, 1993
V. Hoffstein, J. P. Szalai
openalex   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Predictive Value of PLR, PNI, and HALP Scores in Ovarian Cancer Staging. [PDF]

Cancer Manag Res
Genc SO, Gulturk EA, Kurt B.
europepmc   +1 more source

Value of the P-wave signal-averaged ECG for predicting atrial fibrillation after cardiac surgery. [PDF]

, 1993
Jonathan S. Steinberg, S. Zelenkofske, Sharon Wong, M. Gelernt, Robert R. Sciacca, Edith Menchavez   +5 more
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Predictive Value of an Early Diagnosis of Orthostatic Hypotension on Cardiovascular Events. [PDF]

J Clin Hypertens (Greenwich)
Quarti-Trevano F, Cuspidi C, Grassi G.
europepmc   +1 more source

Electrogram patterns predictive of successful catheter ablation of accessory pathways. Value of unipolar recording mode. [PDF]

, 1991
Michel Haı̈ssaguerre, Jean‐François Dartigues, J F Warin, P Le Métayer, P Montserrat, Ratko Salamon   +5 more
openalex   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source