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The relative value of operon predictions [PDF]
For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combination of) the following five criteria: (i) intergenic distance, (ii) conserved gene clusters, (iii) functional relation, (iv) sequence elements and (v) experimental evidence.
Sacha A. F. T. van Hijum+2 more
openaire +4 more sources
Predictive Value of Spirometry in Screening of Children with Respiratory Disease [PDF]
Introduction:The diagnostic value of spirometry in the evaluation of pulmonary function is known; however, the predictive potential of this method has always been undervalued.
Seyed Javad Sayedi+5 more
doaj +1 more source
Intermittent Time Series Demand Forecasting Using Dual Convolutional Neural Networks
Forecasting intermittent demands is challenging due to their irregular and unpredictable demand pattern. This makes the businesses unprepared for upcoming demands, where the conventional methods often fail to predict the demand occurrence pattern ...
Sina Mirshahi+2 more
doaj +1 more source
AST-to-ALT ratio in the first trimester and the risk of gestational diabetes mellitus
BackgroundAspartate aminotransferase-to-alanine transaminase ratio (AST/ALT) has been reported affect the risk of type 2 diabetes (T2DM), but it is uncertain if it has relationship with gestational diabetes mellitus (GDM).ObjectivesOur study aimed to ...
Rongjing An+12 more
doaj +1 more source
Standardized predictive values
The predictive value of a diagnostic test is highlydependent upon disease prevalence. Disease preva-lence, however, varies widely from patient to patient.Since patients in whom the diagnosis is unclear arethe ones most likely to get a diagnostic test, it is help-ful to standardize the predictive value of a diagnostictest to a disease prevalence of 50%.
openaire +3 more sources
The scientific value of explanation and prediction
Abstract Deep neural network models have revived long-standing debates on the value of explanation versus prediction for advancing science. Bowers et al.'s critique will not make these models go away, but it is likely to prompt new work that seeks to reconcile explanatory and predictive models, which could change how we determine what constitutes ...
openaire +2 more sources
Predictive Value of Microdose Pharmacokinetics
Phase 0 microdose trials are exploratory studies to early assess human pharmacokinetics of new chemical entities, while limiting drug exposure and risks for participants. The microdose concept is based on the assumption that microdose pharmacokinetics can be extrapolated to pharmacokinetics of a therapeutic dose.
Alwin D. R. Huitema+5 more
openaire +5 more sources
A Longitudinal Study of the Dynamics of Giftedness
Introduction. The paper presents a longitudinal study nearly a half-century long of the dynamics of giftedness from adolescence to maturity. Giftedness is an individual’s ability for creativity.
Diana B. Bogoyavlenskaya
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Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka+6 more
wiley +1 more source
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley+2 more
wiley +1 more source