Patients who take their symptoms less seriously are more likely to have colorectal cancer
BMC Gastroenterology, 2012 Background People vary in how they respond to symptoms. The purpose of this study was to assess whether serious disease is more likely to be present in patients who report that they take any symptoms less seriously than other people do, and to assess the
Adelstein Barbara-Ann +3 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
On The Predictive Content Of Production Surveys: A Pan-European Study [PDF]
For over forty years, Business Tendency Surveys have been collected in multiple member states of the European Union. Previous research has studied the predictive accuracy of the expectation variables included in those surveys through bivariate, within ...
Croux, C., Dekimpe, M.G., Lemmens, A.
core +4 more sources
THE PREDICTIVE VALUE OF A STUDY CHOICE TEST
INTED Proceedings, 2019 Since 2016, it is mandatory for all future students at the department of Media, Information and Communication, to participate in a study choice test (SCT), prior their enrollment. However, the outcome is not binding and students are still entitled to enter the first year after receiving negative advice. With the help of a structural model, built for my
openaire +1 more source
Validation of c-reactive protein in the early diagnosis of neonatal sepsis in a tertiary care hospital in Kenya. [PDF]
, 2010 Objective: To evaluate utility of C-reactive protein (CRP) in the early diagnosis of neonatal sepsis in a tertiary care Newborn Unit in Kenya. Design: Cross-sectional study. Setting: Newborn Unit, Kenyatta National Hospital.
Kumar, Rashim +3 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Positive Predictive Value of Gen-Probe APTIMA Combo 2 Testing for Neisseria gonorrhoeae in a Population of Women with Low Prevalence of N. gonorrhoeae Infection [PDF]
, 2004 Matthew R. Golden +8 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ARE PULP SENSIBILITY TESTS STILL SENSIBLE? [PDF]
, 2015 Background: Electric and thermal tests are the most commonly employed methods for the diagnosis of pulp health status. The objectives of our study are to assess the validity, yield and accuracy of cold and electric pulp tests in determining pulp ...
Farid, Huma +3 more
core +1 more source