Results 111 to 120 of about 1,276,953 (303)

Diagnostic Tests for Helicobacter Pylori Infection [PDF]

open access: yes, 2008
Helicobacter pylori is a spiral-shaped Gram negative bacterium, has 4-6 flagella, live in microaerophillic condition, has urease, oxidase and catalase enzymes. Helicobacter pylori (H.
Loho, T. (Tonny)
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Use of Skin Testing Screening and Desensitization Before the First Exposure of Rituximab

open access: yesCancer Management and Research, 2021
Lisha Li,1 Lianglu Wang,1 Kai Guan,1 Jun Liu,1 Daobin Zhou,2 Yanbin Zhang,2 Yan Zhang2 1Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Precision ...
Li L   +6 more
doaj  

A Predictive Model for Estimation Risk of Proliferative Lupus Nephritis

open access: yesChinese Medical Journal, 2018
Background: Lupus nephritis (LN) is classified by renal biopsy into proliferative and nonproliferative forms, with distinct prognoses, but renal biopsy is not available for every LN patient.
Dong-Ni Chen   +5 more
doaj   +1 more source

Validation of c-reactive protein in the early diagnosis of neonatal sepsis in a tertiary care hospital in Kenya. [PDF]

open access: yes, 2010
Objective: To evaluate utility of C-reactive protein (CRP) in the early diagnosis of neonatal sepsis in a tertiary care Newborn Unit in Kenya. Design: Cross-sectional study. Setting: Newborn Unit, Kenyatta National Hospital.
Kumar, Rashim   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

THE PREDICTIVE VALUE OF A STUDY CHOICE TEST

open access: yesINTED Proceedings, 2019
Since 2016, it is mandatory for all future students at the department of Media, Information and Communication, to participate in a study choice test (SCT), prior their enrollment. However, the outcome is not binding and students are still entitled to enter the first year after receiving negative advice. With the help of a structural model, built for my
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Innovation through Artificial Intelligence in Triage Systems for Resource Optimization in Future Pandemics

open access: yesBiomimetics
Artificial intelligence (AI) systems are already being used in various healthcare areas. Similarly, they can offer many advantages in hospital emergency services.
Nicolás J. Garrido   +5 more
doaj   +1 more source

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